What is a Double Marker Test and what does it detect?

Hi Viahnu Ji,

Thanks for your question!

The Double Marker Test is a screening test done during pregnancy, usually between the 9th and 13th week, to check the baby’s risk of having certain chromosomal abnormalities — mainly Down syndrome (Trisomy 21), Trisomy 18, and Trisomy 13.

What does the test measure?

The test looks at two markers in the mother's blood:

1. Free Beta hCG (a pregnancy hormone)
2. PAPP-A (Pregnancy Associated Plasma Protein A)

These are combined with other details, such as your age and ultrasound findings (nuchal translucency), to calculate the baby’s risk.

Why is it important?

• It does not diagnose a condition but tells you if there’s a higher or lower chance that your baby might have a genetic issue.
• If the risk is high, further tests like NIPT or amniocentesis may be recommended to confirm.

Is it safe?

Yes, it’s completely safe for both mother and baby — just a simple blood test.

If you or someone you know is expecting and planning this test, we can help you connect with a good specialist, book appointments, or answer any further questions.