Liv 52 Side Effects-Read Expert's Opinion

Written by Hexahealth Care Team, last updated on 23 December 2023
Liv 52 Side Effects-Read Expert's Opinion

Liv 52 is a widely known herbal supplement that is commonly used for promoting liver health and detoxification. However, there are potential Liv 52 side effects that one must be aware of to choose the right course of treatment. 

It may be beneficial for the liver but one must also understand the Liv 52 side effects on kidneys and know the impact of the supplement on the vital organ. Liv 52 may protect the kidneys by reducing oxidative stress and inflammation and enhancing the antioxidant defense system. However, conflicting studies suggest possible adverse side effects of Liv 52.

It is important to note that the available research on the overall effects of Liv 52 is limited and inconclusive, and individual experiences with the supplement may vary.

The following article discusses Liv 52, its common side effects, and its benefits for a better understanding of the disease. Continue reading to know more!

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About Liv 52

Liv 52 is a herbal-mineral remedy renowned for its ability to enhance liver function. It combines herbs with appetiser properties, facilitating better digestion and boosting appetite. The formulation of Liv 52 is specifically designed to offer protection against various forms of liver toxins.

The hepatoprotective effects (ability to prevent damage to the liver) of Liv 52 are well-documented, making it a famous choice for those suffering from liver diseases. By shielding the liver from harm, Liv 52 aids in restoring liver health. However, it is also essential to know the exact Liv 52 side effects to better gauge its impact on the body. 

One of the key advantages of Liv 52 is its ability to counteract a wide range of liver toxins. Whether the damage is caused by chemicals, medications, or alcohol consumption, Liv 52 offers protective action to mitigate the harmful effects on the liver. This is particularly beneficial for individuals who consume alcohol regularly. 

Composition of Liv 52 Tablets

The composition of Liv 52 tablets includes various herbal ingredients carefully selected for their beneficial properties. A single tablet contains specific quantities of different ingredients, as follows:

  1. Caper Bush (Himsra) – Capparis Spinosa: Each tablet contains 65 mg of Caper Bush, known for its hepatoprotective and antioxidant properties.

  2. Wild Chicory (Kasani) – Cichorium Intybus: One Liv 52 tablet contains 65 mg of Wild Chicory, which aids in liver detoxification and digestion improvement.

  3. Mandur Bhasma – Ferric Oxide Calx: LIv 52 contains 33 mg of Mandur Bhasma, a compound derived from Ferric Oxide Calx, which supports liver health.

  4. Black Nightshade (Kakamachi) – Solanum Nigrum: It contains 32 mg of Black Nightshade, known for its hepatoprotective and anti-inflammatory properties.

  5. Arjuna – Terminalia Arjuna: One tablet of Liv 52 contains 32 mg of Arjuna, which helps in liver tissue regeneration and offers cardiac support.

  6. Negro coffee (Kasamarda) – Cassia Occidentalis: Every tablet contains 16 mg of Negro coffee, which aids in liver detoxification and supports digestive health.

  7. Yarrow (Biranjasipha) – Achillea Millefolium: A single Liv 52 tablet contains 16 mg of Yarrow, known for its anti-inflammatory and hepatoprotective properties.

  8. Tamarisk (Jhavuka) – Tamarix Gallica: One tablet contains 16 mg of Tamarisk, which supports liver health and exhibits diuretic properties.

These ingredients are meticulously combined in Liv 52 tablets to provide a comprehensive formulation that promotes liver health, detoxification, digestion, and overall well-being.

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Side Effects of Liv 52

Liv 52 may have potential side effects that need to be considered. Not all individuals experience these side effects. However, it is advised to be aware of possible Liv 52 tablet side effects to select the most appropriate treatment option:

  1. Allergic Reactions: These reactions may manifest as skin rashes, itching, swelling, or difficulty breathing. If signs of an allergic reaction are noticed, immediate medical attention should be sought.

  2. Gastrointestinal Discomfort: Some individuals may experience gastrointestinal issues such as nausea, vomiting, stomach cramps, or diarrhoea when taking Liv 52. These symptoms are generally mild and transient, but if they persist or worsen, discontinue use and consult a healthcare professional.

  3. Kidney Issues: While the available research is limited, there have been concerns about the potential impact of Liv 52 on kidney function. In rare cases, Liv 52 has been associated with renal dysfunction, which is characterised by increased serum creatinine levels, proteinuria, and renal failure. 

    Individuals with pre-existing kidney conditions or those misusing the supplement may be at a higher risk. 
  1. Interactions with Medications: Liv 52 may interact with certain medications, particularly those metabolised by the liver. It is essential to inform a healthcare professional about all the medications, supplements, or herbal remedies being taken to avoid potential interactions.

  2. Pregnancy and Breastfeeding: The safety of Liv 52 during pregnancy and breastfeeding has not been extensively studied. However, it is best to consult with the healthcare provider to understand the potential side effects of Liv 52 on pregnant women and lactating mothers. 

  3. Drug Testing: Liv 52 contains some herbal ingredients that may interfere with specific drug tests. It is essential to inform healthcare professionals or employers about using Liv 52 if undergoing drug testing procedures.

Side Effects of Ingredients of Liv 52

The specific ingredients of Liv 52 may vary depending on the formulation. Below is the list of potential side effects associated with some commonly used ingredients in Liv 52:

  1. Himsra (Caper Bush): Rare side effects may include allergic reactions and stomach upset. 

  2. Kasani (Chicory): Possible side effects can include abdominal discomfort or diarrhoea.

  3. Mandur Bhasma (Ferric Oxide Calx): Excessive or prolonged use may lead to iron overload, which can have adverse effects on the body.

  4. Arjuna (Arjuna Tree): High doses may cause gastrointestinal upset or constipation.

Preventive Measures to Curb The Side Effects of Liv 52

While dealing with the Liv 52 side effects is important, one must also know the preventive measures that reduce the impact of these conditions. Below are some of the most essential measures:

  1. Consult a healthcare professional: Before starting any new supplement, including Liv 52, it is advisable to consult with a healthcare professional or a qualified practitioner. 

  2. Follow recommended dosage: Stick to the recommended dosage as instructed on the packaging or as prescribed by your healthcare provider. 

  3. Inform about allergies or sensitivities: If you have known allergies or sensitivities to any specific ingredients in Liv 52, make sure to inform your healthcare provider.

When To Consult a Doctor?

In certain situations, seeking medical attention when using Liv 52 or experiencing liver-related symptoms is advisable. Here are some instances in which consulting a doctor is recommended:

  1. Severe or Persistent Symptoms: If symptoms such as abdominal pain, jaundice, unexplained weight loss, or persistent fatigue worsen or do not improve with Liv 52 use, it is important to seek medical evaluation.

  2. Existing Liver Conditions: Individuals with pre-existing liver diseases, such as hepatitis, cirrhosis, or liver cancer, should consult their healthcare provider before starting Liv 52 or any other supplement. The doctor can assess the compatibility of Liv 52 with their specific condition and guide its usage.

  3. Medication Interactions: If the person is taking other medications or undergoing treatments, it is crucial to consult a healthcare professional to ensure no potential interactions or contraindications with Liv 52.

  4. Allergic Reactions: If an individual experiences signs of any allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing after taking Liv 52, immediate medical attention should be sought.

  5. Concerns about Kidney Health: While Liv 52's impact on kidney function is inconclusive, those with kidney conditions or concerns about kidney health should consult a doctor before starting Liv 52 to evaluate its potential effects.

In all cases, it is advised to follow the instructions of a healthcare professional who can provide personalised guidance based on an individual's specific health condition and needs.


Liv 52 is a widely used herbal supplement with numerous potential benefits for liver health, but understanding the Liv 52 side effects is also crucial. Prioritise medical advice and consult a healthcare professional before starting Liv 52 or any herbal supplement, especially with concerns about kidney health.

We at HexaHealth can help you better understand the potential impact of a drug and how well it is likely to treat your specific condition. Our experts take your individual medical history into consideration and suggest the best line of treatment. Reach out to us today!

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Frequently Asked Questions

What is Liv 52 and its role?

Liv 52 is a herbal formulation that is commonly used as a liver support supplement. It is composed of various herbs and natural ingredients that are believed to promote liver health and function.

What are the benefits of Liv 52?

The benefits of Liv 52 are often associated with its potential to support liver function and provide hepatoprotective effects.

Liv 52 is believed to assist in the detoxification process by eliminating toxins from the liver.

Who should not take Liv 52?

While Liv 52 is generally considered safe for most individuals, there are certain groups of people who should avoid taking it.

Due to limited research on the safety of Liv 52 during pregnancy and lactation, it is advisable for pregnant or breastfeeding women to avoid its use.

Is Liv 52 DS good for kidneys?

Liv 52 DS (double strength) is a variant of Liv 52 that contains a higher concentration of herbal ingredients.

While it is generally considered safe, there is limited scientific evidence specifically addressing its impact on kidney health.

What are the side effects of Liv 52 on kidney function?

Adverse effects on kidney function are not commonly reported with Liv 52. However, individual reactions and sensitivities may vary.

Some herbal ingredients in Liv 52, such as Chicory and Black Nightshade, have been traditionally used in Ayurvedic medicine for kidney-related conditions.

Can Liv 52 cause kidney damage or kidney failure?

There is no substantial evidence to suggest that Liv 52 can cause kidney damage or kidney failure.

However, if you have pre-existing kidney problems, it is important to exercise caution and consult a healthcare professional before starting any new supplement.

Is Liv 52 safe for people with kidney problems?

Liv 52 is generally safe for individuals with kidney problems. However, it is advised to consult a healthcare professional before using Liv 52 or any dietary supplement, especially if you have existing kidney issues, as comprehensive clinical studies on Liv 52's effects, specifically on kidney function, are limited.

How does Liv 52 affect kidney function?

The impact of Liv 52 on kidney function is not well-studied. While Liv 52 is primarily known for its effects on liver health, it contains various herbal ingredients that may have indirect effects on kidney function.

What precautions should be taken while using Liv 52 in people with kidney disease?

If you have kidney disease or any kidney-related issues, it is important to exercise caution when using Liv 52.

Precautions that should be taken include consulting a healthcare professional before starting Liv 52, especially if you have advanced kidney disease or are undergoing dialysis.

What are the symptoms of Liv 52-induced kidney damage?

Liv 52-induced kidney damage is not commonly reported. However, if you experience any unusual symptoms while taking Liv 52, including changes in urine output, persistent abdominal pain, or swelling, it is important to seek medical attention promptly.

How long does it take for Liv 52 to affect kidney function?

The exact timeline for Liv 52 to affect kidney function is unknown since there is limited research specifically addressing this aspect.

It is advisable to monitor your kidney function regularly if you have pre-existing kidney issues and are using Liv 52.

Can Liv 52 be used in people with kidney stones or other kidney-related issues?

Liv 52 can be used in people with kidney stones or other kidney-related issues, but caution is advised.

It is essential to consult with a healthcare professional before using Liv 52 if you have kidney stones or a history of kidney problems.

Is there a safe dosage of Liv 52 for people with kidney problems?

There is no established safe dosage of Liv 52 specifically for people with kidney problems.

It is crucial to consult with a healthcare professional who can evaluate your kidney function, consider your medical history, and recommend an appropriate dosage or alternative treatment if necessary.

Are there any alternatives to Liv 52 for people with kidney issues?

There are alternative supplements and treatments available for individuals with kidney issues.

It is recommended to consult with a healthcare professional specialising in kidney health or a nephrologist to explore alternative options that are specifically tailored to your condition.


All the articles on HexaHealth are supported by verified medically-recognized sources such as; peer-reviewed academic research papers, research institutions, and medical journals. Our medical reviewers also check references of the articles to prioritize accuracy and relevance. Refer to our detailed editorial policy for more information.

  1. Ganesh S, Joshi N, Jain MK, Sharma L, Desai A, Rafiq M, et al. Clinical and Safety Evaluation of Liv.52 in Alcoholic Liver Disease: A Review. Gastroenterology Insights [Internet]. 2022 Dec 1 [cited 2023 Jul 10];13(4):377–86. link
  2. de Silva HA, Saparamadu PAM, Thabrew MI, Pathmeswaran A, Fonseka MMD, de Silva HJ. Liv.52 in alcoholic liver disease: a prospective, controlled trial. Journal of Ethnopharmacology. 2003 Jan;84(1):47–
  3. Cimen O, Eken H, Keskin Cimen F, Cekic AB, Kurt N, Ozbek Bilgin A, Suleyman B, Suleyman H, Mammadov R, Pehlivanoglu K, Kurnaz E. The effect of Liv-52 on liver ischemia reperfusion damage in rats. BMC Pharmacol Toxicol. 2020 Jan 3;21(1):2. doi: 10.1186/s40360-019-0380-0. PMID: 31900219; PMCID: PMC694link
  4. Kaláb M, Krechler T. Vliv hepatoprotektiva LIV 52 na jaterní poskozeni [The effect of the heptoprotective agent LIV 52 on liver damage]. Cas Lek Cesk. 1997 Dec 17;136(24):758-60. Czech. PMID:
  5. Philips CA, Augustine P, Rajesh S, Y PK, Madhu D. Complementary and Alternative Medicine-related Drug-induced Liver Injury in Asia. J Clin Transl Hepatol. 2019 Sep 28;7(3):263-274. doi: 10.14218/JCTH.2019.00024. Epub 2019 Sep 2. PMID: 31608219; PMCID:
  6. Iroanya OO, Adebesin OA, Okpuzor J. Evaluation of the Hepato and Nephron-Protective Effect of a Polyherbal Mixture using Wistar Albino Rats. J Clin Diagn Res. 2014 Jun;8(6):HC15-21. doi: 10.7860/JCDR/2014/5875.4501. Epub 2014 Jun 20. PMID: 25121002; PMCID:
  7. Chauhan BL, Kulkarni RD. Effect of Liv.52, a herbal preparation, on absorption and metabolism of ethanol in humans. Eur J Clin Pharmacol. 1991;40(2):189-91. doi: 10.1007/BF00280076. PMID:

Updated on : 23 December 2023


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HexaHealth Care Team

HexaHealth Care Team brings you medical content covering many important conditions, procedures falling under different medical specialities. The content published is thoroughly reviewed by our panel of qualified doctors for its accuracy and relevance.

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