Hydroquinone Tretinoin Mometasone Furoate Cream

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Medically Reviewed by Dr. Aman Priya Khanna
Written by Sangeeta Sharma, last updated on 3 January 2024
Hydroquinone Tretinoin Mometasone Furoate Cream

Hydroquinone Tretinoin Mometasone Furoate cream - the pathway to radiant skin! With the power of three ingredients, this cream effectively addresses various skin concerns. The cream works harmoniously to fade dark spots, enhance skin texture, and renew skin cells. 

Suitable for various skin types, Hydroquinone Tretinoin and Mometasone Furoate cream is the key to unlocking a confident, vibrant appearance. But what are its uses, and are there any side effects? If you are wondering the same thing, continue reading to learn more about the cream’s uses, side effects, precautions, and more. 

Class of Medicine

Butyric acid derivatives

Condition Treated

Melasma

Dosage

Once daily at night

Formulation

Hydroquinone, Tretinoin, Mometasone

Over-the-Counter Medicine

No

Habit Forming

No

About Hydroquinone Tretinoin Mometasone Furoate Cream

Hydroquinone Tretinoin Mometasone Furoate cream is a topical skincare product that combines three active ingredients: Hydroquinone, Tretinoin, and Mometasone Furoate. Each ingredient specifically addresses various skin concerns. This makes the cream a comprehensive solution for improving skin tone, texture, and overall appearance.

  1. Hydroquinone: It is a skin-lightening agent that helps reduce the appearance of hyperpigmentation. The condition occurs when the skin produces excess melanin, the pigment responsible for skin colour. Hydroquinone works by inhibiting melanin production.

  2. Tretinoin: This ingredient belongs to the class of retinoids (man-made vitamin A). It is widely used to promote skin cell turnover and renewal. It helps in the rejuvenation of the skin. 

  3. Mometasone: It belongs to the class of corticosteroids with anti-inflammatory properties. It works by inhibiting the release of certain chemicals that cause redness, swelling, itching, and irritation in the skin.

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Hydroquinone Tretinoin Mometasone Furoate Cream Needs

Dermatologists, and healthcare professionals prescribe the cream for various skin concerns. Hydroquinone Tretinoin and Mometasone Furoate cream uses include the following:

  1. Melasma (brown or blue-grey patches on the skin)

  2. Psoriasis (an autoimmune skin disorder that causes itchy, scaly patches)

  3. Wrinkles 

  4. Age spots

  5. Tiny bumps and dry patches on the skin

  6. Light brown patches on the skin

  7. Skin inflammation

  8. Skin itching

  9. Skin discolouration

  10. Allergic reactions

  11. Acne

Hydroquinone Tretinoin Mometasone Furoate Cream Benefits

Hydroquinone Tretinoin Mometasone Furoate cream offers several benefits due to the combined effects of its active ingredients. Here are some of the potential benefits of using this cream under the guidance of a healthcare professional:

  1. Reduces Hyperpigmentation: The hydroquinone component targets excessive melanin production, helping to fade dark spots, melasma, and other forms of hyperpigmentation. This results in a more even skin tone.

  2. Renews Skin: Tretinoin encourages the renewal of skin cells, helping in the natural exfoliation of the skin’s outer layer. This reveals fresher, younger-looking skin and improves overall skin radiance.

  3. Treats Acne: By reducing oil production in the skin, Tretinoin prevents clogged pores, reducing acne-related inflammation. It promotes shedding dead skin cells, decreasing pimples, whiteheads, and blackheads. 

  4. Reduces Inflammation: Mometasone’s anti-inflammatory properties can help soothe itching, redness, and irritation associated with various skin conditions.

Directions to Apply

Mometasone Furoate Hydroquinone and Tretinoin cream is for external use only. A healthcare professional should guide the usage of the cream. The general directions for Hydroquinone Tretinoin & Mometasone Furoate cream use are as follows: 

  1. Cleanse: Use a mild soap or gentle cleanser to wash the face, removing dirt or makeup. Pat the skin dry. 

  2. Application: Take a pea-sized amount of the cream on the fingertip and gently apply it to the affected areas. Avoid getting the cream in the nose, eyes, mouth, ears, or vagina. 

  3. Frequency: Apply the cream as advised by the healthcare provider. Generally, the doctor might recommend using it once daily at night.

Route of Administration

Hydroquinone Tretinoin Mometasone Furoate cream is administered through the cutaneous route. This means that the cream is applied directly to the skin. The cream is meant to be used externally and should not be ingested or applied to mucous membranes (such as the eyes, mouth, or inside the nose). 

Dosage Information 

A qualified healthcare professional provides dosage information for Hydroquinone Tretinoin Mometasone Furoate cream. The typically recommended dosage for the cream is once daily at night. While initial recovery may be witnessed in two weeks, full results may appear 2-3 months after regular use. 

Missed Dose

If an individual misses a dose, they should apply the cream as soon as they remember. However, if it is almost time for the next scheduled application, individuals must skip the missed dose and continue their regular dosing schedule. Applying too much cream at once can increase the risk of irritation.

Overdose

Using more Hydroquinone Tretinoin Mometasone Furoate cream than prescribed can lead to an overdose or an increased risk of side effects. It is important to follow the prescribed dosage and usage instructions to ensure the safety and effectiveness of treatment. If someone has overapplied the cream, they should wipe the excess medicine with cotton or tissue.

Precautions While Using the Cream

Hydroquinone Tretinoin Mometasone Furoate cream requires certain precautions to ensure safety and achieve the best possible results. Some important precautions include:

  1. Follow Prescribed Duration: Always use the cream exactly as the healthcare provider or dermatologist prescribes. Follow their recommended dosage, application frequency, and duration of use. Only use the cream 6-8 weeks after consulting the healthcare provider. 

  2. Sun Protection: Tretinoin in the cream can increase the skin’s sensitivity to sunlight. Therefore, the cream should always be used with sun-avoidance measures, like using sunscreens (SPF 30 or higher) and wearing protective clothing. 

  3. Pregnancy and Breastfeeding: A woman should consult her healthcare provider before using this cream if she is pregnant or breastfeeding. Certain ingredients may not be recommended during pregnancy or while breastfeeding.

  4. Children: Hydroquinone Tretinoin Mometasone Furoate cream is not recommended for children below 12 years of age. 

  5. Ulcerated Skin or Wounds: The cream should not be applied to cuts, burns, or infected areas of the skin. 

  6. Avoid Contact With Sensitive Areas: Avoid getting the cream in the eyes, mouth, or inside the nose. If contact occurs accidentally, rinse thoroughly with water.

  7. Avoid Smoking: Individuals should avoid smoking or going near naked flames as the fabric in contact with the cream can easily catch fire.

Side Effects of Hydroquinone Cream

Like any medication, Hydroquinone Tretinoin Mometasone Furoate cream can cause side effects. However, not everyone will experience them. 

It is important to be aware of possible side effects and communicate with the healthcare provider regarding any concerns. Some potential Hydroquinone Tretinoin and Mometasone Furoate cream side effects include:

  1. Skin Irritation: Mild to moderate irritation is a common side effect, especially when first using the cream. This may include a tingling or burning sensation on the skin.

  2. Redness of the Skin: Redness is a common reaction to the cream. It may become noticeable shortly after application. 

  3. Itchiness: Another common side effect of the cream is itchiness. Individuals might have itchy skin after application and an urge to scratch. 

  4. Skin Reaction: Some individuals may experience a change in the skin’s appearance or sensation after applying the cream. Skin reactions may include a range of effects, including redness, dryness, peeling, flaking, or an overall change in skin texture.

  5. Allergic Reaction: While rare, allergic reactions to any of the ingredients in the cream are possible. Signs may include:

    1. Rash

    2. Itching

    3. Swelling

    4. Severe dizziness

    5. Difficulty breathing

  6. Soreness: It is a general feeling of discomfort or tenderness in the treated area. This could result from skin irritation or other factors related to the medication.

Managing Side Effects

The severity of Hydroquinone Tretinoin Mometasone Furoate cream side effects can vary from person to person. If someone experiences severe or persistent side effects, they can take the following steps to manage the same:

  1. Discontinue Use: Individuals should stop using the cream if side effects persist. 

  2. Rinse With Water: If the cream comes in contact with areas like eyes, mouth, nose, or ears, rinse the areas thoroughly with water. 

  3. Cool Compresses: Individuals can use a cool, damp cloth to help soothe redness or itching on the skin. However, one should not rub or scratch the treated areas.

  4. Consult a Healthcare Professional: It is best to consult a healthcare provider if the side effects are persistent or cause discomfort. They may suggest adjusting the application frequency or prescribing additional treatments to manage side effects.

Drug Interaction

Drug-Drug Interaction

Drug interactions can affect the medicines’ effectiveness, increase the risk of side effects, or alter how they work in the body. 

When using Hydroquinone Tretinoin and Mometasone Furoate cream, be aware of potential interactions with prescription and over-the-counter medications. The cream may interact with the following drugs:

  1. Photosensitising Agents: Aminolevulinic acid, verteporfin

  2. Retinoids: Isotretinoin

  3. Topic Antibiotics: Benzoyl peroxide 

  4. Psoralens: Methoxsalen

  5. Keratolytic Agents: Salicylic acid, sulphur

  6. Sensitiser: Methyl aminolevulinate

  7. Antiseptic: Resorcinol

Drug-Food Interaction

Hydroquinone Tretinoin Mometasone Furoate Cream is a topical medication. Therefore, it generally has a minimal risk of direct drug-food interactions. 

Drug-Disease Interaction

When using Hydroquinone Tretinoin Mometasone Furoate Cream, it is important to be aware of potential interactions between the medication and any underlying medical conditions the person may have. Before using the cream, individuals should inform their doctor if they have the following conditions: 

  1. Asthma

  2. Sulphite allergy

  3. Acne

  4. Rosacea (redness and bumps on the face)

  5. Perioral dermatitis (red rash on the skin around the mouth)

  6. Skin thinning

  7. General itching

  8. Ulcerated skin

  9. Cold sores

  10. Chickenpox

  11. Diabetes

  12. Warts (small, noncancerous growths on the skin)

  13. Shingles (a viral infection resulting in a painful rash)

  14. Eczema (skin becomes dry, itchy, and bumpy)

  15. Other skin conditions

Storage of Hydroquinone Tretinoin Mometasone Furoate Cream

Proper storage of Hydroquinone Tretinoin Mometasone Furoate cream is important to maintain its effectiveness and ensure its safety. Here are some guidelines for storing the cream:

  1. Cool and Dry Place: Store the cream in its original container and keep it in a cool and dry place. 

  2. Avoid Direct Sunlight: The cream should be stored away from direct sunlight as it can destroy the medical potency of the cream. 

  3. Close the Lid Tightly: Ensure the lid is securely closed after each use to prevent air and moisture from entering the container.

  4. Keep Away from Children and Pets: When not in use, the cream should be stored away from children and pets to prevent ingestion. 

  5. Check Expiry Date: Always check the expiration date on the packaging before using the cream. Do not use the cream if it has expired. 

Diet and Lifestyle Guidance

Maintaining a healthy diet and lifestyle can complement the treatment of Hydroquinone Tretinoin Mometasone Furoate Cream and contribute to optimal skin health. Here are some dietary and lifestyle tips to consider while using the cream:

  1. Stay Hydrated: Drinking adequate water helps hydrate the skin and support its natural functions.

  2. Sun Protection: Hydroquinone Tretinoin Mometasone Furoate cream can increase the skin’s sensitivity to the sun. Therefore, individuals should wear sunscreen, protective clothing, and a wide-brimmed hat to protect the skin from sunburn. 

  3. Regular Exercise: Regular physical activity helps improve circulation, support overall health, and boost self-esteem. Take a shower immediately after exercise. 

  4. Avoid Harsh Products: During the use of cream, avoid using other products that may irritate, like:

    1. Shampoo

    2. Skin cleansers

    3. Harsh soaps

    4. Hair colours

    5. Hair removers

    6. Skin products with alcohol, astringent, or lime

Price of Hydroquinone Tretinoin Mometasone Furoate Cream

The price of the cream can vary based on the brand, quantity, and local pharmacy or healthcare provider. The approximate price range of the cream is Rs 110 to Rs 450. Contact a local pharmacy for the accurate price of Hydroquinone Tretinoin Mometasone Furoate cream in India.

Takeaway

Hydroquinone Tretinoin Mometasone Furoate cream addresses skin concerns like hyperpigmentation, acne, and inflammation. This topical treatment enhances skin texture and tone through a combination of active ingredients. 

Are you looking for effective ways to treat hyperpigmentation or melasma? HexaHealth provides comprehensive support to individuals dealing with skincare issues. Our expert dermatologists offer guidance. Schedule your appointment TODAY! 

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Frequently Asked Questions

What is Hydroquinone Tretinoin Mometasone Furoate cream?

Hydroquinone Tretinoin Mometasone Furoate cream is a dermatological formulation that addresses hyperpigmentation, acne, and skin inflammation under medical guidance. It combines three ingredients:

  1. Hydroquinone for skin lightening

  2. Tretinoin for texture improvement

  3. Mometasone Furoate for inflammation reduction

Is hydroquinone a steroid?

No, hydroquinone is not a steroid. It is a skin-lightening or bleaching agent that treats hyperpigmentation by reducing melanin production.

What is Hydroquinone Tretinoin Mometasone Furoate cream used for?

Hydroquinone Tretinoin Mometasone Furoate cream treats various skin concerns, such as:

  1. Melasma

  2. Hyperpigmentation

  3. Acne

  4. Inflammation

  5. Wrinkles 

  6. Age spots

  7. Other skin conditions

How does Hydroquinone Tretinoin Mometasone Furoate cream work?

Hydroquinone Tretinoin and Mometasone Furoate cream works by combining three active ingredients. Hydroquinone lightens pigmentation, Tretinoin enhances skin texture, and Mometasone Furoate reduces inflammation.

What are the benefits of using Hydroquinone Tretinoin Mometasone Furoate cream?

Hydroquinone Tretinoin Mometasone Furoate cream’s combined formulation addresses multiple skin concerns, promoting a clearer and more even complexion. It offers several benefits, including:

  1. Reduction of hyperpigmentation

  2. Improved skin texture

  3. Diminished acne

  4. Reduced inflammation

Are there any side effects of Hydroquinone Tretinoin Mometasone Furoate cream?

The side effects of the cream are typically mild. However, individual responses may vary. These side effects may include:

  1. Skin Irritation

  2. Redness of the Skin

  3. Itchiness 

  4. Skin Reaction

  5. Allergic Reaction

  6. Soreness

What is the price of Hydroquinone Tretinoin Mometasone Furoate cream?

Hydroquinone Tretinoin Mometasone Furoate cream price can vary depending on brand, quantity, and retailer. One must check with pharmacies or healthcare providers for specific pricing information.

How to use Hydroquinone Tretinoin Mometasone Furoate cream effectively?

To use Hydroquinone Tretinoin Mometasone Furoate cream effectively. Typically, the effective use of the cream includes the following steps:

  1. Apply a thin layer of Hydroquinone Tretinoin Mometasone Furoate cream on clean skin once daily at night.

  2. Avoid contact with eyes, mouth, and mucous membranes. 

  3. Avoid sun exposure.

Can Hydroquinone Tretinoin Mometasone Furoate cream be used for acne?

Yes, Hydroquinone Tretinoin Mometasone Furoate cream can be used for acne. Its combined ingredients treat acne by reducing inflammation and improving skin texture. Individuals should consult a healthcare provider for guidance on usage and suitability.

Is Hydroquinone Tretinoin Mometasone Furoate cream suitable for all skin types?

Hydroquinone Tretinoin Mometasone Furoate cream may suit various types of skin. However, individual reactions can vary. Therefore, one must always consult a healthcare provider to determine its suitability for a specific skin type.

Are there any alternatives to Hydroquinone Tretinoin Mometasone Furoate cream?

Yes, there are alternatives to Hydroquinone Tretinoin Mometasone Furoate cream. Cysteamine is an alternative active ingredient that can be used to reduce pigmentation. It acts by inhibiting melanin production.

Can Hydroquinone Tretinoin Mometasone Furoate cream be bought online without a prescription?

Hydroquinone Tretinoin Mometasone Furoate cream is a prescription medicine. Therefore, it cannot be bought without a prescription from the doctor. You can buy Hydroquinone Tretinoin Mometasone Furoate cream online after consulting a doctor for proper usage.

Do Hydroquinone Tretinoin and Mometasone Furoate creams make skin sensitive to sunlight?

Yes, the combination of Hydroquinone, Tretinoin, and Mometasone Furoate in the cream can increase skin sensitivity to sunlight. Proper sun protection is essential during its use to prevent sunburn and potential skin damage. This may include using sunscreen and wearing protective clothes.

Does HYDROQUINONE+MOMETASONE+TRETINOIN cause skin irritation?

Yes, Hydroquinone, Mometasone, and Tretinoin can potentially cause skin irritation, especially when starting the treatment. Common side effects may include mild redness, itching, and peeling. One must consult their healthcare provider if irritation is severe or persistent.

Can I use a moisturiser with HYDROQUINONE+MOMETASONE+TRETINOIN?

Hydroquinone, Mometasone, and Tretinoin can make the skin more sensitive to extreme weather. Therefore, using a moisturiser daily is advised to protect the skin from damage. However, it is best to consult a doctor before using any moisturiser with Hydroquinone, Mometasone, and Tretinoin.

Is HYDROQUINONE+MOMETASONE+TRETINOIN used to treat diaper rash?

No, Hydroquinone, Mometasone, and Tretinoin cream is not typically used to treat diaper rash. Using the cream for diaper rash can make the ingredients pass through the skin easily, leading to adverse effects. The cream is primarily indicated for conditions like hyperpigmentation, acne, and skin inflammation.

How long should I use HYDROQUINONE+MOMETASONE+TRETINOIN?

You should use Hydroquinone, Mometasone, and Tretinoin for as long as the doctor recommends. The initial improvement may be seen in two weeks. However, you should consult a doctor before using the cream for more than 6-8 weeks. 

Does HYDROQUINONE+MOMETASONE+TRETINOIN affects the working of hormonal contraceptives?

Hormonal contraceptives like birth control pills, skin patches, injections, vaginal rings, and implants can worsen melasma. Instead, it is better to use non-hormonal birth control like condoms. However, it is advised to consult a doctor before choosing the right contraceptives while getting treatment with Hydroquinone, Mometasone, and Tretinoin.

What are the instructions for the storage and disposal of Hydroquinone+Mometasone+Tretinoin?

The instructions for storing and disposing Hydroquinone+Mometasone+Tretinoin are as follows:

  1. Store in a cool and dry place, away from direct sunlight and moisture. 

  2. Close the lid tightly. 

  3. Keep out of reach of children and pets. 

  4. Dispose of any unused or expired medication. 

Will Hydroquinone+Mometasone+Tretinoin be more effective if taken more than prescribed?

No, Hydroquinone+Mometasone+Tretinoin will not be more effective if taken more than prescribed. Overusing the cream can cause too much medicine to be absorbed in the body, leading to skin thinning and other side effects. Following the prescribed usage guidelines is important to minimise side effects and achieve the intended benefits. 

References

All the articles on HexaHealth are supported by verified medically-recognized sources such as; peer-reviewed academic research papers, research institutions, and medical journals. Our medical reviewers also check references of the articles to prioritize accuracy and relevance. Refer to our detailed editorial policy for more information.


  1. Route of Administration.link
  2. Merative, Micromedex®. Fluocinolone, Hydroquinone, And Tretinoin (Topical Application Route) Proper Use - Mayo Clinic [Internet]. www.mayoclinic.org. [cited 2023 Aug 11].link
  3. Sheliya K, Shah K, Kapupara P. Development and validation of analytical method for simultaneous estimation of mometasone furoate, hydroquinone and tretinoin in topical formulation by RP-HPLC. Available online wwwjocprcom Journal of Chemical and Pharmaceutical Research [Internet]. 2014 [cited 2024 Jalink
  4. Fluocinolone; Hydroquinone; Tretinoin skin cream [Internet]. Cleveland Clinic. [cited 2024 Jan 3].link

Updated on : 3 January 2024

Reviewer

Dr. Aman Priya Khanna

Dr. Aman Priya Khanna

MBBS, DNB General Surgery, Fellowship in Minimal Access Surgery, FIAGES

12 Years Experience

Dr Aman Priya Khanna is a well-known General Surgeon, Proctologist and Bariatric Surgeon currently associated with HealthFort Clinic, Health First Multispecialty Clinic in Delhi. He has 12 years of experience in General Surgery and worke...View More

Author

Sangeeta Sharma

Sangeeta Sharma

BSc. Biochemistry I MSc. Biochemistry (Oxford College Bangalore)

6 Years Experience

She has extensive experience in content and regulatory writing with reputed organisations like Sun Pharmaceuticals and Innodata. Skilled in SEO and passionate about creating informative and engaging medical conten...View More

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