Inflammatory Bowel Disease: Symptoms, Causes, Treatment

Inflammatory Bowel Disease

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Inflammatory Bowel Disease

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Do you know that children and teenagers account for most inflammatory bowel disease cases in India? This chronic condition is rising in the country and poses significant challenges to those affected. But what are the signs of this disorder?

The inflammatory bowel disease symptoms include abdominal pain, diarrhoea, and rectal bleeding. Want to know more? Read on to learn about IBD diagnosis, prevention, treatment options, and other important details!

Disease Name

Inflammatory Bowel Disease

Symptoms

Abdominal pain, diarrhoea, rectal bleeding

Causes

Genetic predisposition, air pollution, food additives

Diagnosis

Blood tests, stool tests, endoscopic procedures

Treated By

Gastroenterologists

Treatment Options

Medication, dietary modifications, surgical intervention

What is IBD

Inflammatory Bowel Disease (IBD) is a chronic medical disorder of the gastrointestinal tract. It involves a dysregulated immune response that mistakenly attacks the digestive tract. This leads to inflammation, ulcers, and other complications.

Inflammatory Bowel Disease Types

The inflammatory bowel disease involves a group of chronic conditions that affect the digestive tract. There are two main types of IBD:

  1. Ulcerative Colitis: Characterised by irritation, swelling, and ulcers. It arises in the walls of the colon (the longest portion of the large intestine) and rectum (end of the colon).

  2. Crohn's Disease: Involves inflammation of the lining in the digestive tract. It can occur in the mouth or the anus, often penetrating deep into the affected tissues.

Inflammatory Bowel Disease Grades

Inflammatory bowel disease progression can be categorised into grades ranging from mild to severe. Each level indicates the severity of symptoms and the extent of inflammation. The stages are as follows:

Grade

Indication

Grade 0

Minimal inflammation, no neutrophils (white blood cells) and ulceration

Grade 1

Moderate/severe chronic inflammation, neutrophils and ulceration absent

Grade 2

Few neutrophils without ulceration

Grade 3

Moderate/severe neutrophil infiltrate, no ulceration

Grade 4

Ulceration present


Inflammatory Bowel Disease Symptoms and Signs

Inflammatory bowel diseasesymptoms are primarily associated with the digestive tract and can vary in severity and duration. Recognising these indicators helps in timely diagnosis and treatment:

  1. Abdominal Discomfort: Pain and cramping are the earliest and most persistent symptoms, localised in the lower abdomen.

  2. Diarrhoea: Frequent and urgent bowel movements, sometimes accompanied by blood in stool, ulcers, and mucous.

  3. Weight Loss: Occurs due to decreased appetite and malabsorption of nutrients.

  4. Fatigue: Persistent tiredness, possibly due to anaemia and malnutrition.

  5. Fever: Temperature may get high during flare-ups or due to the immune response to inflammation.

Inflammatory Bowel Disease Causes

The exact inflammatory bowel disease causes remain unclear. However, it can result from a complex interplay of genetic, environmental, and immunological factors. 

Inflammatory Bowel Disease Risk Factors

Various factors can increase an individual's susceptibility to developing inflammatory bowel disease. Identifying them is crucial for understanding the disease's onset and progression:

  1. Family history: Having a close relative with IBD enhances the chances of developing the condition due to shared genetic predispositions.

  2. Age: IBD most commonly occurs in adolescents and young adults. People aged 60 years and older are also more prone to developing this disease.

  3. Diet: High intake of processed foods and saturated fats significantly increases risk of IBD. 

  4. Smoking: This doubles the risk of developing Crohn's disease by disrupting the functioning of the immune system and the intestinal barrier.

  5. Medications: Prolonged use of NSAIDs has been associated with an increased risk of developing IBD.

  6. Immune System Dysfunction: Abnormal immune responses in the gastrointestinal tract can lead to chronic inflammation.


Prevention of Inflammatory Bowel Disease


As stated before, the exact causes of IBD are unknown. However, lifestyle changes may help reduce the risk of developing the condition or alleviate symptoms. Check the table below to understand the preventive measures.

Do's

Don'ts

Eat balanced diet

Smoke tobacco

Stay hydrated

Consume alcohol

Yoga and meditation practise

Take antibiotics and pain medicines

Regular exercise

Eat high-fat and sugary foods

Practise good hygiene

Stay stressful


How is an inflammatory bowel disease diagnosed?

Inflammatory bowel disease diagnosis involves a multifaceted approach combining patient history, clinical examination, and various investigations. The step-by-step breakdown is provided below.

  1. Patient History: The physician will gather detailed information about the patient's symptoms. This includes the onset and frequency of abdominal pain, diarrhoea, rectal bleeding, and other relevant symptoms. A family history of IBD or other autoimmune diseases is also assessed.

  2. Clinical Examination: Physical tests may reveal abdominal tenderness, palpable masses, or malnutrition. A digital rectal examination is performed to assess for rectal bleeding, inflammation, or masses.

  3. Investigations: Certain examinations may be conducted by the medical professional to diagnose the issue more clearly. These include:

  1. Blood Tests: This involves a complete blood count (CBC) to assess for anaemia or infection. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are done to measure inflammation levels.

  2. Stool Tests: Helps check for signs of infection, inflammation, or blood in the stool.

  3. Endoscopic Procedures: Colonoscopy or flexible sigmoidoscopy may be performed to visualise the colon and terminal ileum directly. Doctors obtain tissue samples (biopsy) for microscopic examination and assess disease severity and extent.  

  4. Imaging Tests: Ultrasound, CT scan, or MRI may be performed to visualise the gastrointestinal tract.

Note: Specific tests advised or prescribed may vary depending on individual patient characteristics, symptoms, and clinical findings. 

How to prepare for the doctor’s consultation?

Preparing for a doctor's consultation is essential to make the most of the appointment and ensure effective communication with the healthcare provider. The key steps to consider are:

  1. The doctor will inquire about the medical history and perform necessary examinations. 

    1. Expect the doctor to ask about medical concerns, symptoms, and medical history.

    2. Be prepared for a physical examination, which may involve palpation, auscultation, or other diagnostic procedures.

    3. Discuss treatment options.

  1. During medical consultation, asking queries can enhance the understanding of health conditions.

    1. Are there any lifestyle changes or alternative medicine that could help manage my condition

    2. What are the available treatment options for my condition?

    3. What are the benefits and potential side effects of each treatment option?

Inflammatory Bowel Disease Treatment

When managing inflammatory bowel disease, various treatment options can be considered. These address symptoms and improve quality of life. The overview of the different approaches is as follows:

Nonsurgical Options

In managing IBD, nonsurgical options contribute significantly to alleviating symptoms and improving quality of life.

  1. Home Remedies / Naturopathy: For acute pain relief, applying heat packs to the abdomen can help alleviate discomfort. 

  2. Lifestyle Changes: Avoiding dairy, spicy or high-fibre foods with adequate water or herbal tea intake is recommended. Regular exercise can reduce inflammation. 

  3. Ayurveda and Homoeopathy: It may offer symptom relief for some individuals. However, efficacy varies and should be used under the guidance of a qualified practitioner.

  4. Medications: Aminosalicylates, corticosteroids, immunomodulators, and biologic therapies targeting specific inflammatory pathways.

Surgery

It may be considered for severe cases of IBD that do not respond to traditional treatment. Common procedures include colectomy (removal of part or all of the colon) and strictureplasty (widening narrow segments of the intestine).

Special Cases

Pregnant women and children with IBD require specialised care to manage symptoms while ensuring safety.

Note: The selection of treatment methods depends on the patient’s health condition and doctor's opinion.

Estimated Costs of Inflammatory Bowel Disease Treatment

The estimated costs of treating Inflammatory Bowel Disease (IBD) can vary widely depending on factors such as the severity of the condition. A general overview of potential expenses associated with IBD treatment are:

Treatment Options (Surgical)

Cost Estimate Range

Colectomy 

₹ 70,000 - ₹ 1,75,000

Strictureplasty

₹ 45,000 - ₹ 80,000

Note: The values listed below are estimated and are subject to change. It can vary based on the treatment location, surgeon, technique used, etc. 

Risks of Delaying Inflammatory Bowel Disease Treatment

Delaying treatment for inflammatory bowel disease causes various complications that significantly impact a patient's health and well-being. The breakdown of the risks associated with postponing treatment is given below.

  1. Increased Risk of Bowel Stenosis: Prolonged inflammation in the intestines can lead to narrowing or stenosis of the bowel. This may cause bowel obstruction and severe abdominal pain.

  2. Fistula and Abscess Formation: Untreated IBD may result in the formation of abnormal connections (fistulas), leading to abscesses and recurrent infections.

  3. Development of Arthritis: Inflammation can extend beyond the digestive tract, leading to joint swelling. This causes pain, stiffness, and reduced mobility.

  4. Skin Conditions: IBD can be associated with various dermatological manifestations, including psoriasis, which may worsen with untreated inflammation.

When to Consult a Doctor?

Knowing indications to consult a doctor ensures timely management and prevent potential complications. The scenarios that warrant consultation with a healthcare professional are:

  1. Persistent abdominal pain or cramping

  2. Frequent diarrhoea or blood in stool

  3. Unexplained weight loss

  4. Low-grade fever (99.5 to 100 F)

  5. Fatigue or weakness

  6. Recurring nausea or vomiting

  7. Changes in bowel habits for more than a week

Diet for Inflammatory Bowel Disease

An inflammatory bowel disease diet involves eating foods that can help manage symptoms and promote gut health. Below is a guide to food choices that emphasises both what to include and what to avoid.

Food Items to Eat

Food Items to Avoid

Cooked vegetables (e.g., potatoes) and eggs

Raw vegetables (e.g., broccoli, cabbage)

Ripe fruits (e.g., bananas, applesauce)

Raw fruits (e.g., berries, citrus fruits)

Oats and barley

Spicy foods 

Nut butter (e.g., almond butter, peanut butter)

High-fibre cereals and breads

Low-fat dairy products (e.g., yoghourt, cottage cheese)

Full-fat dairy products (e.g., whole milk, cheese)

Takeaway

Living with inflammatory bowel disease presents challenges, as its unpredictable nature can significantly impact daily life. However, understanding the triggers, coupled with effective management strategies, can assist in easing the issue.

At HexaHealth, we recognise the complexities of IBD and the importance of personalised care. We provide inflammatory bowel disease treatment to help patients effectively manage their condition. So, why wait? Contact us today!

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FAQs for Inflammatory Bowel Disease

What is inflammatory bowel disease?

Inflammatory Bowel Disease (IBD), a chronic inflammatory issue of the digestive tract. It encompasses disorders such as Crohn's disease and ulcerative colitis. They cause symptoms like abdominal pain, diarrhoea, and rectal bleeding.

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What are the causes of inflammatory bowel disease?

Inflammatory Bowel Disease (IBD) arises from a combination of genetic, environmental, and immunological factors. The key causes include:

  1. Genetic predisposition

  2. Dysregulated immune response

  3. Environmental triggers

  4. Gut microbiota dysbiosis

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What are the symptoms of inflammatory bowel disease?

Inflammatory Bowel Disease (IBD) manifests through various symptoms affecting the digestive tract. The common indicators are:

  1. Abdominal pain and cramping

  2. Persistent diarrhoea

  3. Rectal bleeding

  4. Weight loss

  5. Fatigue

  6. Fever

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How is inflammatory bowel disease diagnosed?

Diagnosing Inflammatory Bowel Disease (IBD) involves medical history evaluation, physical examination, and various diagnostic tests. The overview is given below.

  1. Medical history assessment

  2. Physical examination

  3. Blood tests

  4. Stool tests

  5. Imaging scans (e.g., CT scan, MRI)

  6. Endoscopic procedures (e.g., colonoscopy, upper endoscopy)

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What are the treatment options for inflammatory bowel disease?

Treatment options for inflammatory bowel disease aim to reduce inflammation and improve quality of life. The available interventions are:

  1. Medication: Immunomodulators, biologic therapies

  2. Dietary modifications: Low-residue diet, avoiding trigger foods

  3. Lifestyle changes: Stress management, regular exercise

  4. Surgical intervention: Colectomy, strictureplasty

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Is inflammatory bowel disease curable?

The condition can be either Crohner's disease or ulcerative colitis and develops due to genetic or metabolic risk factors. Inflammatory bowel disease (IBD) can be managed with medication, lifestyle changes, and surgical interventions.

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What is the difference between Crohn's disease and ulcerative colitis?

Crohn's disease and ulcerative colitis are parts of inflammatory bowel disease (IBD). However, they differ in the location and nature of inflammation. Crohn's disease may impact any part of the digestive tract. In contrast, ulcerative colitis primarily involves the colon and rectum.

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Can stress trigger inflammatory bowel disease flare-ups?

Yes, stress can trigger inflammatory bowel disease (IBD) flare-ups because of its impact on the immune system and gut function. While stress alone may not cause IBD, managing stress levels is crucial in reducing the severity of flare-ups.

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Can IBS be cured?

No, Irritable Bowel Syndrome (IBS) cannot be cured. However, its symptoms can be managed effectively with dietary modifications, medication, and treatment interventions.

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Are there any dietary recommendations for managing IBD?

Managing Inflammatory Bowel Disease (IBD) often involves dietary modifications to alleviate symptoms and support overall digestive health. The general dietary recommendations are as follows:

  1. Consume a low-fibre diet.

  2. Avoid trigger foods such as spicy foods and dairy.

  3. Incorporate easily digestible foods like cooked vegetables and ripe fruits.

  4. Stay hydrated.

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What medications are commonly used to treat IBD?

Inflammatory Bowel Disease (IBD) is often managed with a combination of medications aimed at controlling symptoms. Common medications include:

  1. Aminosalicylates 

  2. Corticosteroids 

  3. Immunomodulators 

  4. Biologic therapies

  5. Antibiotics

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How does inflammatory bowel disease affect pregnancy?

Inflammatory Bowel Disease (IBD) can impact pregnancy by increasing the risk of complications such as preterm birth, low birth weight, and flare-ups during gestation. It necessitates close monitoring and management by healthcare professionals.

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What are the risk factors for developing IBD?

Several factors can contribute to the development of Inflammatory Bowel Disease (IBD). The key reasons include:

  1. Family history of IBD

  2. Age

  3. Ethnicity

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Are there any alternative therapies for inflammatory bowel disease?

While conventional medical treatments are used to manage inflammatory bowel disease, one may explore alternative therapies. These include:

  1. Probiotics

  2. Herbal supplements

  3. Acupuncture

  4. Mind-body techniques (e.g., yoga, meditation)

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Can inflammatory bowel disease lead to colon cancer?

Yes, individuals with inflammatory bowel disease, particularly ulcerative colitis, have higher risk of developing colon cancer. Regular monitoring and early detection through colonoscopies are crucial for managing this risk effectively.

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What are the complications of untreated inflammatory bowel disease?

Untreated inflammatory bowel disease can lead to various complications, potentially worsening the patient's health. The potential complications include:

  1. Bowel obstruction

  2. Malnutrition

  3. Fistulas

  4. Abscesses

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How often should someone with inflammatory bowel disease have follow-up appointments?

Individuals with inflammatory bowel disease (IBD) typically require frequent follow-up appointments.  A common recommendation is to schedule visits every 14 days for closer monitoring.

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Can inflammatory bowel disease be prevented?

Inflammatory bowel disease (IBD) cannot be entirely prevented due to its complex and multifactorial nature. However, adopting a healthy lifestyle, avoiding smoking and maintaining a balanced diet may help reduce the risk of developing the condition.

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How does smoking affect inflammatory bowel disease?

Smoking triggers the symptoms and increases the severity of IBD. Quitting the habit is generally recommended for overall health and to improve disease management.

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What role does genetics play in inflammatory bowel disease?

Genetics significantly impact inflammatory bowel disease (IBD) development. Certain genetic variations like HLA increase susceptibility to the condition. Individuals with a family history of IBD are more prone to developing the condition due to shared genetic predispositions.

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Is surgery ever necessary for treating inflammatory bowel disease?

Surgery may be necessary for treating inflammatory bowel disease (IBD) in cases of severe complications. This may include:

  1. Bowel obstruction

  2. Fistulas

  3. Abscesses

  4. Failure of medical management

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References

All the articles on HexaHealth are supported by verified medically-recognized sources such as; peer-reviewed academic research papers, research institutions, and medical journals. Our medical reviewers also check references of the articles to prioritize accuracy and relevance. Refer to our detailed editorial policy for more information.


  1. Mayo Clinic. Inflammatory bowel disease (IBD) - Symptoms and causes [Internet]. Mayo Clinic. 2022. link
  2. Centers for Disease Control and Prevention. CDC -What is inflammatory bowel disease (IBD)? - Inflammatory Bowel Disease - Division of Population Health [Internet]. www.cdc.gov. 2018.link
  3. Stages of Crohn’s Disease | Healthline [Internet]. Healthline. 2012.link
  4. Johns Hopkins Medicine. Inflammatory Bowel Disease (IBD) [Internet]. www.hopkinsmedicine.org. 2024.link
  5. What is inflammatory bowel disease (IBD)? | IBD [Internet]. www.cdc.gov. 2022.link
  6. Inflammatory bowel disease: Causes, symptoms, and treatments [Internet]. www.medicalnewstoday.com. 2020.link
  7. Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham [Internet]. www.massgeneralbrigham.org.link
  8. Seyedian S, Nokhostin F, Dargahi Malamir M. A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease. Journal of Medicine and Life [Internet]. 2019;12(2):113–22.link
  9. Inflammatory Bowel Disease: Symptoms, Treatment & Diagnosis [Internet]. Cleveland Clinic.link
  10. Lifestyle and diet if you have IBD [Internet]. Mayo Clinic Health System.link
  11. Patel M, Patel K, Gupta S. Effects of Ayurvedic treatment on forty-three patients of ulcerative colitis. AYU (An International Quarterly Journal of Research in Ayurveda). 2010;31(4):478.link
  12. Hashash JG, Kane S. Pregnancy and Inflammatory Bowel Disease. Gastroenterology & hepatology [Internet]. 2015;11(2):96–102.link
  13. Rosen MJ, Dhawan A, Saeed SA. Inflammatory Bowel Disease in Children and Adolescents. JAMA Pediatrics [Internet]. 2015 Nov 1;169(11):1053.link
  14. Lee D, Koo JS, Choe JW, Suh SJ, Kim SY, Hyun JJ, et al. Diagnostic delay in inflammatory bowel disease increases the risk of intestinal surgery. World Journal of Gastroenterology. 2017 Sep 21;23(35):6474–81.link
  15. Five Inflammatory Bowel Disease Symptoms You Should Never Ignore [Internet]. NYU Langone News. [cited 2024 Apr 5].link
  16. University of California San Francisco. Nutrition tips for inflammatory bowel disease [Internet]. ucsfhealth.org.link
  17. Jain M, Venkataraman J. Inflammatory bowel disease: An Indian perspective. Indian Journal of Medical Research. 2021;153(4):421.link
  18. Choe MY, Wright R, Parian A. Follow-up Care in Inflammatory Bowel Disease. Gastroenterology Nursing. 2021 May;44(3):E48-R58.link
  19. Ye BD, McGovern DPB. Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility. Expert Review of Clinical Immunology. 2016 Jun 15;12(10):1091–107.link

Updated on : 5 April 2024

Reviewer

Dr. Aman Priya Khanna

Dr. Aman Priya Khanna

MBBS, DNB General Surgery, Fellowship in Minimal Access Surgery, FIAGES

12 Years Experience

Dr Aman Priya Khanna is a well-known General Surgeon, Proctologist and Bariatric Surgeon currently associated with HealthFort Clinic, Health First Multispecialty Clinic in Delhi. He has 12 years of experience in General Surgery and worke...View More

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Sparshi Srivastava

Sparshi Srivastava

B.Tech Biotechnology (Bansal Institute of Engineering and Technology, Lucknow)

2 Years Experience

An ardent reader, graduated in B.Tech Biotechnology. She was previously associated with medical sciences secondary research and writing. With a keen interest and curiosity-driven approach, she has been able to cont...View More

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