Dermoid Cyst vs Sebaceous Cyst - What is the Difference?

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Medically Reviewed by Dr. Priyanka Sharma
Written by Charu Shrivastava, last updated on 5 January 2023
Dermoid Cyst vs Sebaceous Cyst - What is the Difference?

A cyst is a fluid or air-filled sack of membraneous tissue. These cysts can develop almost anywhere in your body or under the skin. There are several types of cysts, most of which are non-cancerous or benign. Two such cysts of the skin include dermoid cysts and sebaceous cysts. These non-cancerous pouches of tissues are filled with fluid or other material that looks like small peas under the surface of the skin. 

Wondering what these cysts are and how are they different? The following blog provides detailed information on dermoid cysts vs sebaceous cysts to help you understand the difference. 

What is a Dermoid Cyst?

A dermoid cyst is a sac-like growth of normal tissue under the skin, usually present at birth. 

  1. It is a bump or lump that may contain fluid, nerves, hair, bone, sweat glands, skin, or teeth. 
  2. Dermoid cysts can develop anywhere on your body or even deeper inside the body. 
  3. There are several types of dermoid cysts based on their location. The most common types include:
    1. Periorbital Dermoid Cyst: Forms near the outer edge of your left or right eyebrow.
    2. Ovarian Dermoid Cyst: Forms in or on your ovary.
    3. Spinal Dermoid Cyst: Forms on your spine.

Other rare types of dermoid cysts include:

  1. Epibulbar (on the surface of your eye)
  2. Intracranial (in your brain)
  3. Nasal sinus (inside your nose)
  4. Orbital (around the bones of your eye socket). 

Initially, a dermoid cyst may seem like a tumour. However, these cysts are usually harmless. You may need surgery to remove them as they do not resolve on their own. 

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What is a Sebaceous Cyst?

A sebaceous cyst is an atypical growth in your body containing liquid or semiliquid material. 

  1. It is a yellow or white lump on your skin that is usually harmless and can develop at any age. 
  2. This cyst originates from the sebaceous glands and can occur anywhere on the body (primarily on the face, neck, and torso) except your palms and soles. It does not develop in the palms and soles because there are no sebaceous glands present on your palms and soles. 
  3. A sebaceous cyst can go away by itself, or you may need to get it treated. However, if left unchecked, it may become uncomfortable.

Dermoid vs Sebaceous Cyst

Dermoid and sebaceous cysts are two non-cancerous cysts that differ in terms of their origin, content, causes, and symptoms. 

Difference between Dermoid Cyst and Sebaceous Cyst based on the Origin

Parameter

Dermoid Cyst

Sebaceous Cyst

Origin

Dermis (the middle layer of the skin)

Excess secretion of sebum (an oily, waxy substance) in the sebaceous glands

Difference between Dermoid cyst and Sebaceous Cyst based on the Content

Parameter

Dermoid Cyst

Sebaceous Cyst

Content

Consists of a greasy yellow material, fluid, bone, hair, skin, sweat glands, nerves, or teeth

Consists of Sebum

Difference between Dermoid Cyst and Sebaceous Cyst based on Causes and Risk Factors

Parameter

Dermoid Cyst

Sebaceous Cyst

Causes When the skin layers do not grow together properly during fetal development
  1. Blockage or damage to the sebaceous gland o
  2. Cell damage during surgery
  3. Genetic conditions like basal cell nevus syndrome or Gardner’s syndrome

Risk Factors

Children under 5
  1. Genetics
  2. Male gender
  3. High levels of testosterone
  4. Swollen hair follicles
  5. Skin trauma

Difference between Dermoid Cyst and Sebaceous Cyst based on Diagnosis

Parameter

Dermoid Cyst

Sebaceous Cyst

Diagnosis
  1. Physical exam
  2. CT scan or MRI
  3. Pelvic ultrasound or transvaginal ultrasound
  1. Physical exam
  2. Ultrasound
  3. CT scan
  4. Punch biopsy

How is Sebaceous Cyst and Dermoid Cyst treated?

Treatment of Dermoid Cyst

Surgical removal is the only treatment option for a dermoid cyst. The severity of the surgery depends on the type of cyst:

  1. Periorbital Dermoid Cyst Surgery: The surgeon removes the cyst through a small incision to ensure as little scarring as possible. 
  2. Ovarian Dermoid Cyst Surgery: The surgeon performs an ovarian cystectomy (a minimally invasive surgery) to remove only the cyst. However, if the cyst is large, they may also need to remove the ovary. 
  3. Spinal Dermoid Cyst Surgery: The surgeon performs microsurgery (with a surgical microscope and precise instruments) while you are asleep from anaesthesia.

Treatment of Sebaceous Cyst

If the cyst is small and not bothersome, there is no need for treatment. However, if the cyst is large, inflamed, tender, or causes hair loss on the scalp, the doctor may drain or surgically remove it. Methods to remove a sebaceous cyst include:

  1. Conventional Wide Excision: This method removes the cyst completely but leaves a long scar. 
  2. Laser-aided Excision: The cyst is drained by making a small hole with a laser. 
  3. Minimal Excision: The surgeon removes the cyst using a smaller incision to ensure minimal scarring. However, it carries a risk of the cyst returning.
  4. Punch Excision: The surgeon removes the cyst and normal skin around it with a cookie-cutter-like punch tool.

Takeaway

While a dermoid cyst and a sebaceous cyst may seem similar, they are quite different. Knowing the difference between them is important to get them treated appropriately. In summary, the basic difference is their origin. A dermoid cyst is found in the dermis. On the other hand, a sebaceous cyst occurs due to excessive sebum secretion. 

If you experience the symptoms of a dermoid or sebaceous cyst mentioned above, you can consult with an HexaHealth expert TODAY! Our team of doctors will answer all your queries regarding your symptoms and causes. Furthermore, we will help you find the right hospital and surgeon for effective diagnosis and treatment.

Frequently Asked Questions

What is the difference between an epidermoid cyst and a sebaceous cyst?

An epidermoid cyst is present in the superficial of the uppermost layer of the skin, whereas a sebaceous cyst originates from the sebaceous glands. Furthermore, an epidermoid cyst is filled with dead skin cells, while a sebaceous cyst is filled with yellowish oily material. 

Is a dermoid cyst soft or hard?

 A dermoid cyst can either be soft and slightly compressible or feel as hard as a rock. This happens because the amount of bone on both sides of the cyst can vary in height and thickness. 

What is the difference between lipoma and a dermoid cyst?

A dermoid cyst is a fluid-filled lump most often found in the neck or head, whereas a lipoma is a lump filled with fats, mostly found on the neck, shoulders, chest, back, arms, buttocks, and thighs. Furthermore, a dermoid cyst is usually small in size, whereas a lipoma is larger in size. 

What does a dermoid cyst look like?

Dermoid cysts look like small lumps under the skin. This lump may be skin-coloured or slightly blue. Furthermore, the skin around the cyst may have a yellowish tint. Dermoid cysts can occur anywhere on the body. 

What is the difference between dermoid and epidermoid cysts?

While both dermoid and epidermoid cysts are slow-growing and non-cancerous, they are different. A dermoid cyst is found in the dermis (middle layer of the skin), whereas an epidermoid cyst is present in the superficial of the uppermost layer of the skin. 

What is a sebaceous cyst filled with?

Sebaceous cysts form within sebaceous glands. Sebaceous glands produce oil to coat your hair and skin. Glands that get blocked or damaged can cause sebaceous cysts filled with sebum (an oily, waxy substance excreted by sebaceous glands). 

What happens if a dermoid cyst is not removed?

Untreated dermoid cysts typically do not cause any harm. However, if they grow, it can cause complications like:

  1. Infection
  2. Nearby bone damage
  3. Cyst rupture
  4. Injury to the spinal cord or spinal nerves
  5. Ovarian torsion (twisting of the ovaries)

How do I know if I have a dermoid cyst?

A dermoid cyst may appear as a painless lump in the affected area. A cyst near the eyebrow may produce pressure on the eyeball, causing pain and visual problems. If a cyst gets infected, it may become red and swollen. 

At what size should a dermoid cyst be removed?

Dermoid cysts grow slowly (1 to 2 mm per year), for which surgery is often not recommended. Your doctor may recommend removing a dermoid cyst when it reaches a size of about 5 cm.

Can I stick a needle in a sebaceous cyst?

While a doctor may insert a thin needle to drain the cyst, you should not stick a needle in a sebaceous cyst yourself. This can cause redness, swelling, and infection. You should consult a doctor to get the lumps examined and make sure they are not serious. 

Can you pop a sebaceous cyst?

No, you should not pop a sebaceous cyst yourself or with the help of another person. Popping a sebaceous cyst can cause it to come back, requiring more extensive dermatological treatment in future. Moreover, it can lead to an infection. 

Why do dermoid cysts grow back?

Surgery is an effective way to remove dermoid cysts. However, a cyst can grow back if it is not removed completely.

What does an epidermoid cyst look like?

An epidermoid cyst looks like a small, round lump under the skin that usually forms on the neck, face, or trunk. Sometimes, a thick, smelly, yellow fluid drains from the cyst. Moreover, if the cyst gets inflamed or infected, it may cause redness, tenderness, and swelling in the affected area.

Do epidermoid cysts need to be removed?

Epidermoid cysts are slow-growing and painless bumps that rarely cause problems or require treatment. You may decide to get the cyst removed if it is painful, infected, or ruptured. You may also get it removed if the look of the cyst bothers you. 

What is an epidermoid cyst filled with?

Epidermoid cysts are caused due to injury or irritation to the skin. They are filled with protein keratin. Keratin is a thick, yellow substance that drains from the cysts sometimes. 

What does a sebaceous cyst look like?

 A sebaceous cyst looks like a yellow or white lump slowly growing under the skin. It is usually soft enough to touch. Sebaceous cysts are usually harmless and do not hurt. However, you may look out for signs of infections. The affected area may become red and warm if the cyst becomes inflamed.

Updated on : 5 January 2023

Reviewer

Dr. Priyanka Sharma

Dr. Priyanka Sharma

MBBS, DNB Plastic Surgery

14 Years Experience

Dr Priyanka Sharma is a well-known Plastic, Reconstructive and Aesthetic Surgeon associated with HealthPort Clinic in Delhi. She has 14 years of experience in Plastic, Reconstructive and Aesthetic surgery and worked as an expert Plastic,...View More

Author

Charu Shrivastava

Charu Shrivastava

BSc. Biotechnology I MDU and MSc in Medical Biochemistry (HIMSR, Jamia Hamdard)

2 Years Experience

Skilled in SEO and passionate about creating informative and engaging medical content. Her proofreading and content writing for medical websites is impressive. She creates informative and engaging content that educ...View More

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