Dr. Mitesh Shetty

Dr Mitesh Shetty is a highly skilled clinical geneticist and laboratory leader in Bangalore with 25 years of experience in medical genetics, prenatal diagnosis, genetic counselling, and genomic medicine. He currently serves as Head of Department and Consultant – Medical Genetics at Manipal Hospital.

With over 15,000 clinical evaluations and genetic counselling sessions and personal supervision of more than 70,000 genetic and screening reports, Dr Mitesh holds a rare distinction of combining senior clinical geneticist expertise with active laboratory governance. He is widely regarded among the best medical geneticists in Bangalore for his depth in clinical genetics, laboratory standardisation, and academic leadership.

Patients and families seeking genetic evaluation for chromosomal disorders, hereditary cancers, prenatal screening, recurrent pregnancy loss, neuromuscular conditions, or rare genetic diseases can consult Dr Mitesh Shetty for structured assessment and evidence-based genetic counselling. He consults in English, Hindi, Kannada, and Tulu.

Area of Expertise

Comprehensive medical genetics care is delivered across prenatal diagnosis, genetic counselling, laboratory genomics, and oncogenetics.

Prenatal Diagnosis and Genetic Screening

Advanced screening and diagnostic pathways are provided for expectant parents and families planning pregnancy.

• First and second trimester prenatal screening
• Non-Invasive Prenatal Testing (NIPT/NIPS)
• Pre-implantation Genetic Testing (PGT)
• Prenatal genetic counselling
• Newborn screening supervision

Clinical Genetics and Dysmorphology

Structured clinical evaluation is provided for patients with suspected genetic conditions across all age groups.

• Down syndrome evaluation
• Skeletal dysplasias and dysmorphology assessment
• Intellectual disability and developmental delay evaluation
• Chromosomal disorder diagnosis
• Recurrent pregnancy loss and infertility-related genetic workup
• Pre-marital genetic screening and consanguinity counselling

Neuromuscular and Neurodegenerative Genetics

Expert evaluation is offered for inherited conditions affecting the nervous system and muscles.

• Duchenne Muscular Dystrophy (DMD)
• Spinal Muscular Atrophy (SMA)
• Huntington's disease
• Developmental and epileptic encephalopathies
• Dravet syndrome

Oncogenetics and Cancer Risk Assessment

Structured genetic counselling and risk evaluation is provided for hereditary cancer syndromes.

• Hereditary breast and ovarian cancer risk assessment
• Cancer genomic array analysis
• Somatic mutation analysis
• Oncogenetic counselling

Laboratory Genomics and Advanced Genetic Testing

A full-spectrum genetic laboratory is supervised with direct oversight on reporting and clinical correlation.

• Karyotyping
• Fluorescence In Situ Hybridisation (FISH)
• Chromosomal Microarray Analysis (CMA)
• Next-Generation Sequencing (NGS) including exome sequencing
• Sanger sequencing
• Biochemical screening tests
• Sperm aneuploidy testing

Haematological Genetics

Specialised testing and counselling is provided for inherited blood disorders.

• β-Thalassemia diagnosis and carrier screening
• Genetic haemolytic anaemias
• Haemophilia evaluation

Professional Experience

Dr Mitesh Shetty is currently associated with:

• Head of Department and Consultant – Medical Genetics, Manipal Hospital, Old Airport Road, Bengaluru
• Consultant – Medical Genetics, Manipal Hospital, Sarjapur Road, Bengaluru

He has previously served at:

• Consultant, Sri Devaraj Urs Medical College

Credentials, Qualifications, and Registration

Educational Qualifications

• MBBS from Dr D Y Patil Medical College and Hospital, Navi Mumbai in 2001
• MSc in Medical Genetics from University of Glasgow, United Kingdom in 200
• PhD in Medical Genetics from Manipal University

Fellowships and TrainingY Patil Medical College and Hospital, Navi Mumbai in 2001MSc

• Short-term Fellowship in Medical Genetics from York Hill Hospital, Glasgow, UK
• European Board of Medical Genetics (EBMG)

Professional Memberships

• Indian Academy of Paediatrics – Genetics Specialty Chapter
• Indian Society of Human Genetics (ISHG)
• Bangalore Society of Obstetrics and Gynaecology (BSOG)
• Indian Society for Prenatal Diagnosis and Therapy (ISPDT)
• Indian Society of Inborn Errors of Metabolism (ISIEM)
• Molecular Pathology Association of India

Academic Leadership

• Course Director – MSc Genomic Counselling Programme, Manipal Academy of Higher Education (MAHE)
• Course Director – One-Year Fellowship in Molecular Genetic Pathology, MAHE
• Recognised PhD Guide at Manipal Academy of Higher Education
• Guided PhD, M Phil, and MSc students in medical genetics and genetic counselling

Awards and Key Contributions

• First to integrate exome sequencing with whole-genome CNV backbone analysis at institutional level
• Organised CME on "Integrating Genomics into Clinical Practice" and "New Horizons in Medicine Through Genomics"
• Conducted end-to-end hands-on workshops on Chromosomal Microarray Analysis
• Led public awareness initiatives on Down syndrome, autism, thalassemia, cancer genetics, and rare genetic disorders

Selected Talks and Academic Presentations

• "Epigenetics in Personalized Medicine" at PES University (January 2026)
• "Genetic Counselling in Mosaic Embryo" at Gunasheela Conclave 2025
• "CMA in Prenatal Diagnosis" at BHU Varanasi International Conference (March 2025)
• Chairperson – Applications of Genomics in Rare Disorders at MPAICON 2025, CMC Vellore
• "Genomics in IEM" at Sterling Mac, Bangalore (November 2024)
• "Autism: Must Know for All Physicians" organised by MedFlix (June 2024)

Registration

• Karnataka Medical Council – Registration No 97939 since 2013

Book an Appointment

For consultation on prenatal genetic screening, chromosomal disorders, hereditary cancer risk, neuromuscular genetics, recurrent pregnancy loss, consanguinity counselling, or advanced genomic testing (NGS, CMA, FISH, karyotyping), Dr Mitesh Shetty is available at Manipal Hospital Old Airport Road and Manipal Hospital Sarjapur Road. Book your appointment through HexaHealth for a seamless and priority consultation experience.