Dr. Sharat Damodar

Dr Sharat Damodar is a Senior Consultant, Clinical Lead, Director of Adult Haemato-Oncology and BMT, and Clinical Director at Mazumdar Shaw Medical Centre, Narayana Health City, Bangalore with 33 years of experience in clinical haematology, haemato-oncology, and bone marrow transplantation.

He holds a DM in Clinical Haematology from Christian Medical College, Vellore, one of Asia's foremost haematology training programmes, and has performed over 1,200 bone marrow and stem cell transplants across his career.

He is the Chairman of the Oncology Collegium at Narayana Health and was recently elected Secretary of the Indian Society of Blood and Marrow Transplant (ISBMT), a national body of 190 BMT centres reporting close to 5,000 transplants annually.

Patients seeking expert bone marrow transplant in Bangalore, trusted leukaemia and lymphoma treatment in HSR Layout, or advanced CAR-T cell therapy in Bommasandra will find Dr Damodar at Mazumdar Shaw Medical Centre, Bommasandra and Narayana Multispeciality Hospital, HSR Layout.

He established the BMT unit at Narayana Health City in 2004 and has conducted the largest number of allogeneic bone marrow transplants in Karnataka.

He has 51 peer-reviewed publications with 364 citations on ResearchGate and has been invited to speak at the ETHealthworld India Oncology Leadership Summit 2026 and the WBMT Symposium on Cell Therapy 2025.

He consults in English, Hindi, Telugu, Kannada, and Tamil, ensuring clear communication for patients from across India.

Specialty Areas and Treatments

Dr Sharat Damodar delivers comprehensive clinical haematology, haemato-oncology, and cellular therapy care through evidence-based and multidisciplinary treatment approaches with dedicated subspecialty focus on bone marrow transplantation and CAR-T cell therapy.

Bone Marrow Transplantation in Bangalore

Dr Damodar is one of Karnataka's most experienced bone marrow transplant physicians with over 1,200 transplants performed since 2004:

• Autologous Stem Cell Transplant for multiple myeloma, lymphoma, and selected solid tumours with published quality-of-life outcomes data
• Allogeneic Stem Cell Transplant for leukaemia, MDS, aplastic anaemia, and thalassaemia with published outcomes from ISCTR registry
• Haploidentical Stem Cell Transplant with TCR alpha/beta and CD19 depletion with published outcomes data
• Matched Unrelated Donor (MUD) Transplant with published HLA match likelihood data for Indian patients
• Cord Blood Transplantation for paediatric and adult haematological malignancies
• Pre-Transplant Evaluation including HLA typing, organ function, and fitness workup
• Post-Transplant Care GVHD management, infection surveillance, and engraftment monitoring
• ABO Mismatch Transplantation with published research on impact on transplant outcomes

CAR-T Cell Therapy in Bangalore

Dr Damodar is one of Karnataka's pioneers in CAR-T cell therapy with published Indian CAR-T data and international conference presentations:

• CAR-T Cell Therapy for relapsed and refractory B-cell lymphoma
• CAR-T Cell Therapy for relapsed and refractory ALL
• Varnimcabtagene Indian Data with published experience
• Patient Selection and Eligibility Assessment for CAR-T therapy
• Post-CAR-T Monitoring CRS and neurotoxicity management

Blood Cancer Treatment in Bommasandra

Dr Damodar manages all categories of haematological malignancies through chemotherapy, targeted therapy, immunotherapy, and stem cell transplantation:

• Acute Myeloid Leukaemia (AML) intensive induction and consolidation with published genomic outcomes data from India
• Acute Lymphoblastic Leukaemia (ALL) paediatric and adult protocols
• Acute Promyelocytic Leukaemia (APL) ATRA and arsenic-based regimens with published granulocytic sarcoma case
• Chronic Myeloid Leukaemia (CML) TKI therapy and monitoring
• Chronic Lymphocytic Leukaemia (CLL) targeted therapy and immunotherapy
• Hodgkin Lymphoma ABVD and escalated regimens
• Non-Hodgkin Lymphoma R-CHOP and novel agents
• Multiple Myeloma proteasome inhibitors, immunomodulatory agents, autologous BMT with published single-centre outcomes
• Myelodysplastic Syndromes (MDS) hypomethylating agents including decitabine with published Indian response data
• Myeloproliferative Neoplasms polycythaemia vera, essential thrombocythaemia, and myelofibrosis

Aplastic Anaemia and Bone Marrow Failure in HSR Layout

Dr Damodar has published extensively on aplastic anaemia management including immunosuppressive therapy, ATG, and stem cell transplantation:

• Aplastic Anaemia immunosuppressive therapy with ATG and cyclosporine with published outcomes
• Immunosuppressive Therapy for Aplastic Anaemia with published guidelines paper in JAPI
• Predicting Response to Immunosuppressive Therapy using EGFR and TWIST1 expression with published research
• Allogeneic SCT for Aplastic Anaemia with published ISCTR registry outcomes
• Inherited Bone Marrow Failure Syndromes Fanconi anaemia and related conditions

Thalassaemia and Haemoglobinopathies in Bangalore

Dr Damodar has published landmark data on stem cell transplantation for thalassaemia from south India:

• Thalassaemia Major allogeneic SCT with published national outcomes data
• Haploidentical SCT for Thalassaemia with novel TCR alpha/beta CD19 depletion conditioning
• Beta Thalassaemia transfusion protocols and iron chelation
• Unstable Haemoglobin Disease haploidentical SCT with published case
• MRI-Based Liver Iron Quantification in thalassaemia patients undergoing BMT with published research
• First-Cousin BMT in Thalassaemia with published thymogam conditioning data

Bleeding and Clotting Disorders in Bangalore

Dr Damodar has published research on haemophilia surgical management and acquired coagulation disorders:

• Haemophilia A and B factor replacement and surgical haemostasis with published aortic valve replacement outcomes
• Acquired Haemophilia with published rare case of antibodies against both Factor VIII and IX
• Immune Thrombocytopenia (ITP) IVIg, dapsone, steroids with published 90-patient dapsone study
• Heparin-Induced Thrombocytopenia (HIT) scoring system comparison with published prospective study
• Thrombotic Disorders including antiphospholipid syndrome
• Eosinophilia and Valvular Heart Disease with published case series

Immunotherapy in Haematology

Dr Damodar has contributed to multiple international clinical trials on IVIg therapy for ITP:

• Intravenous Immunoglobulin (IVIg) for ITP with published multinational Phase III trial data
• Immunosuppressive Therapy for aplastic anaemia and autoimmune cytopenias

Qualifications

• MBBS from St Johns Medical College, Bangalore (1993)
• MD Internal Medicine from St Johns Medical College, Bangalore (1999)
• DNB Internal Medicine from National Board of Examination, New Delhi (1999)
• DM Clinical Haematology from Christian Medical College and Hospital, Vellore (2004)

Dr Damodar holds active medical council registration with the Karnataka Medical Council (Reg. No. 36140, 1993).

Awards and Recognitions

• Secretary, Indian Society of Blood and Marrow Transplant (ISBMT), a national body of 190 BMT centres, 2026
• Chairman's Award for Best Doctor, Narayana Health City, 2015
• Visitor Training Program (VTP) Awardee, American Society of Haematology (ASH), 2015 to 2016
• Established BMT unit at Narayana Health City, 2004, one of Karnataka's first dedicated BMT programmes
• Conducted the largest number of allogeneic bone marrow transplants in Karnataka
• Speaker, ETHealthworld India Oncology Leadership Summit 2026, Mumbai
• Speaker, WBMT Symposium on Cell Therapy, November 2025

Milestones and Clinical Achievements

• Over 1,200 bone marrow and stem cell transplants performed across career
• Established BMT unit at Narayana Health City, Bangalore in April 2004
• Chairman of Oncology Collegium, Narayana Health Network
• Clinical Director, Mazumdar Shaw Medical Centre from May 2015 onwards
• In charge of DNB programme in Clinical Haematology, 4 seats per year at NRS Medical College
• Steering Committee Member, Indian Stem Cell Transplant Registry (ISCTR)
• General Secretary, Karnataka Chapter of ISHBT
• 51 peer-reviewed publications with 364 citations on ResearchGate covering BMT, aplastic anaemia, thalassaemia, AML, ITP, and CAR-T cell therapy
• Internationally invited faculty at BMT and haematology conferences across India and globally
• Ex-Chairman, Hospital Transfusion Committee, Mazumdar Shaw Medical Centre
• Member, Hospital Infection Control Committee, Mazumdar Shaw Medical Centre
• Member, Hospital Drug Formulary Committee, Mazumdar Shaw Medical Centre

Research and Publications

Dr Damodar has 51 peer-reviewed publications with 364 citations on ResearchGate across haematology, BMT, aplastic anaemia, thalassaemia, AML, ITP, and CAR-T cell therapy. Selected publications include:

• Hematopoietic Stem Cell Transplant Outcomes in Patients with Acute Myeloid Leukemia from a Tertiary Care Center in South India, Biology of Blood and Marrow Transplantation, March 2020
• Haematopoietic Stem Cell Transplant Outcomes in Patients with Thalassemia Major from a Tertiary Care Center in South India, Biology of Blood and Marrow Transplantation, March 2020
• Quantification of Liver Iron Overload: Correlation of MRI and Liver Tissue Biopsy in Pediatric Thalassemia Major Patients Undergoing Bone Marrow Transplant, Indian Journal of Hematology and Blood Transfusion, February 2020
• Safety and Efficacy of Intravenous Immunoglobulin (Flebogamma 10% DIF) in Patients with Immune Thrombocytopenic Purpura, Immunotherapy, November 2018
• Improved Outcomes with Allogeneic Stem Cell Transplantation for Aplastic Anaemia Using HLA Identical Sibling Donors: The Indian Stem Cell Transplant Registry Experience, Blood, December 2015
• Higher Than Reported Response Rates to Decitabine Observed in Indian AML Patients: Is There a Genomic Basis, Blood, December 2014
• Pre-Transplant Reduction of Isohemagglutinin Titres by Donor Type Plasma Infusion Does Not Reduce the Incidence of Pure Red Cell Aplasia in Major ABO-Mismatched Transplants, Bone Marrow Transplantation, September 2005
• Immunosuppressive Therapy for Aplastic Anaemia, Journal of Association of Physicians of India, March 2015
• Stem Cells in Hemato-Oncology, Journal of Stem Cells and Regenerative Medicine, December 2006

His Narayana Health blog contributions include:

• How CAR T-Cell Therapy is Changing Blood Cancer Treatment, Narayana Health Blog, November 2024
• Understanding the Impact of Genetic Testing on Cancer: Detection, Prevention, and Treatment, Narayana Health Blog, August 2024

Professional Memberships

• Secretary, Indian Society of Blood and Marrow Transplant (ISBMT)
• Life Member, Indian Society of Haematology and Blood Transfusion (ISHBT)
• General Secretary, Karnataka Chapter of ISHBT
• Member, Asia Pacific Blood and Marrow Transplantation Group (APBMT)
• Member, American Society for Blood and Marrow Transplantation (ASBMT)
• Steering Committee Member, Indian Stem Cell Transplant Registry (ISCTR)
• International Member, American Society of Haematology (ASH)

About Narayana Health, Bangalore

Narayana Health is one of India's largest and most trusted healthcare networks with facilities across 18 cities in India.

Dr Sharat Damodar practises at Mazumdar Shaw Medical Centre, Bommasandra and Narayana Multispeciality Hospital, HSR Layout, Bangalore, offering specialist haematology, bone marrow transplantation, CAR-T cell therapy, and haemato-oncology care accessible across south Bangalore.

Mazumdar Shaw Medical Centre at Narayana Health City is one of India's most advanced dedicated cancer and transplant centres, housing a dedicated BMT unit established in 2004 with one of the highest allogeneic transplant volumes in Karnataka.

Hospital Affiliations in Bangalore

Current Practice

• Mazumdar Shaw Medical Centre, Bommasandra, Bangalore as Senior Consultant, Clinical Lead and Director, Adult Haemato-Oncology and BMT, ₹850
• Narayana Multispeciality Hospital, HSR Layout, Bangalore as Senior Consultant, Clinical Lead and Director, ₹850
• Narayana Clinic, HSR Layout, Bangalore as Senior Consultant

Past Experience

• Narayana Hrudayalaya as Senior Consultant Haematologist and Head, Bone Marrow Transplant Unit (April 2004 onwards)
• Christian Medical College Hospital, Vellore as PG Registrar and Registrar, Department of Haematology (1999 to 2004)
• St Johns Medical College Hospital, Bangalore as PG Registrar, Department of General Medicine (1995 to 1999)
• St Ignatius Hospital, Honavar as Resident Medical Officer (1993 to 1995)

Book an Appointment with Dr Sharat Damodar, Haematologist in Bangalore

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