Dr. Jayanti Mani

Dr Jayanti Mani is a globally acclaimed Neurologist and Epileptologist in Mumbai with a massive 30 years of elite clinical experience in managing drug-resistant seizures and complex epilepsy surgeries.

She currently serves as a Consultant in Neurology at the prestigious Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute in Andheri West, where she established the entire Epilepsy Programme.

She is highly polyglot, fluent in English, Hindi, Marathi, Gujarati, Tamil, and Telugu—ensuring exceptional communication with patients from across India and the globe.

Demonstrating unmatched clinical supremacy, Dr Mani specializes in rescuing patients who suffer from catastrophic, drug-resistant epilepsy.

She has personally executed advanced presurgical evaluations for over 400 complex epilepsy patients and facilitated 80 major brain surgeries, completely curing patients of life-threatening seizures.

She is a master of advanced neurophysiology, utilizing long-term Video EEG monitoring and intraoperative electrical mapping to pinpoint the exact microscopic cluster of misfiring brain cells causing the seizures.

She is specifically trained to manage the neurological safety of patients undergoing Awake Craniotomies for tumor and seizure focus removals.

She is a globally published clinical researcher, authoring chapters in apex neurosurgery textbooks and publishing heavily in journals like Epilepsia and Neurology.

She brings decades of formidable clinical leadership to her practice, having previously established the Epilepsy Program at Bombay Hospital.

Specialty Areas and Treatments

Dr Jayanti Mani provides world-class, technology-driven neurological care, utilizing advanced brain mapping to cure severe seizure disorders when medications fail.

Advanced Epileptology and Seizure Management

She executes highly customized medical protocols for severe neurological misfiring:

• Comprehensive Management of Drug-Resistant (Intractable) Epilepsy
• Advanced Care for Adult and Paediatric Epilepsy Syndromes
• Diagnostic Management of First-Time Seizures and Syncope

Neurophysiology and Brain Mapping

She utilizes high-definition electrode monitoring to map the electrical storms in the brain:

• Advanced Short-Term and Long-Term Video EEG Monitoring
• Intraoperative Electrical Mapping and Cortical Stimulation
• Complex Clinical Neurophysiology Analysis

Epilepsy Surgery and Presurgical Evaluation

She acts as the definitive diagnostic authority prior to complex neurosurgery:

• Comprehensive Presurgical Evaluation for Seizure Focus Localization
• Neurological Management during Awake Craniotomies
• Post-Operative Neurological Rehabilitation

Education and Qualifications

• MBBS — Seth GS Medical College and KEM Hospital, Mumbai
• MD in Internal Medicine — Seth GS Medical College and KEM Hospital, Mumbai
• DM in Neurology — Seth GS Medical College and KEM Hospital, Mumbai
• Fellowship in Epilepsy and Clinical Neurophysiology — Cleveland Clinic Foundation, USA (2005)
• Visiting Fellow in EEG and Clinical Neurophysiology — Kings College, London, UK

Awards and Recognitions

• Best Paper Award — National Epilepsy Conference (2015)
• Joint Secretary — SAMMAN (Indian Epilepsy Association, Mumbai Branch)

Publications and Research

Dr Mani is a globally recognized neuroscience researcher, publishing heavily on seizure classification, brain mapping, and complex epilepsy surgery:

• Luders H, Mani J, et al. (2014). Proposal: different types of alteration and loss of consciousness in epilepsy. Epilepsia.
• Malla B, Mani J. (2012). Surgery for Epilepsy. Ramamurthi and Tandon Textbook of Neurosurgery, 3rd edition.
• Luders HO, Mani J, et al. (2012). Modern technology calls for a modern approach to classification of epileptic seizures and the epilepsies. Epilepsia.
• Mani J, Diehl B, Luders HO, et al. (2008). Evidence for a basal temporal visual language center: cortical stimulation producing pure alexia. Neurology.
• Mani J, Gupta A, Wyllie E, et al. (2006). Postoperative seizures after extratemporal resections and hemispherectomy in pediatric epilepsy. Neurology.
• Mani J, et al. (1999). Multiple sclerosis: experience in neuroimaging era from western India. Neurology India.
• Fong GC, Mani J, et al. (1998). Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike... linkage to chromosome 8q24. American Journal of Human Genetics.

Professional Memberships

• American Academy of Neurology (AAN)
• American Epilepsy Society (AES)
• Indian Academy of Neurology (IAN)
• Indian Epilepsy Association (IEA)

Professional Experience

Dr Jayanti Mani currently practises at the following facilities:

• Consultant, Neurology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute in Andheri West
• Visiting Consultant, Lokmanya Tilak Municipal Medical College, Sion, Mumbai
• Consultant (Former), Bombay Hospital And Medical Research Centre, Marine Lines
• Consultant (Former), Wockhardt Hospital, Mulund
• Visiting Consultant (Former), Kings College, London, UK

Book an Appointment with Dr Jayanti Mani

To book an appointment with Dr Jayanti Mani or to check OPD timings and consultation details at Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute in Andheri West in Mumbai, connect with the HexaHealth team for assistance.