Dr. Upal Sengupta

Dr Upal Sengupta is a Director of Team Nephrology and Consultant in Nephrology and Kidney Transplant at Manipal Hospitals, Mukundapur, Kolkata, with over 23 years of experience in complex kidney transplantation, critical care nephrology, glomerular diseases, and cardio-kidney-metabolic care.

He has completed more than 200 kidney transplantations including ABO-incompatible and highly sensitised transplants, with advanced training in ABO-incompatible transplantation in Tokyo, Japan, and his pioneering research on stem cell therapy in glomerulonephritis has received international recognition.

He consults in English, Hindi, Bengali, and Punjabi.

Area of Expertise

Kidney Transplantation

Patients requiring kidney transplantation including complex and rare transplant scenarios are managed with comprehensive pre and post-transplant care:

• ABO-incompatible kidney transplantation
• Highly sensitised transplant management
• Pre-transplant evaluation and workup
• Post-transplant infection and graft dysfunction management
• Long-term transplant follow-up care

Chronic Kidney Disease

Patients with progressive chronic kidney disease are managed with personalised treatment plans focused on disease progression retardation and quality of life:

• CKD staging and management
• Diabetic kidney disease at all stages
• Protein restriction and nutritional management in CKD
• Rising creatinine evaluation and intervention
• Elderly kidney care

Glomerular and Autoimmune Kidney Disease

Patients with glomerular disorders and autoimmune kidney conditions are evaluated and managed with specialist nephrology expertise:

• SLE nephritis management
• Vasculitis-related kidney disease
• Idiopathic membranous nephropathy
• Glomerulonephritis diagnosis and treatment
• Proteinuria and haematuria evaluation

Critical Care Nephrology

Patients with acute kidney injury and kidney failure in cardiac and liver disease are managed with intensive nephrology and renal replacement support:

• Acute kidney injury management
• Kidney failure in cardiac disease
• Kidney failure in liver disease
• Continuous renal replacement therapy
• Acute on chronic kidney disease management

Cardio-Kidney-Metabolic Care

Patients with integrated cardiovascular, renal, and metabolic disorders are managed with a holistic CKM treatment approach:

• Cardio-kidney-metabolic syndrome management
• Hypertension-related kidney disorder
• Resistant hypertension management
• Metabolic disorder and kidney interaction
• Diabetic kidney disease and cardiovascular risk

Interventional Nephrology and Dialysis

Patients requiring dialysis and interventional nephrology procedures are managed with comprehensive haemodialysis, peritoneal dialysis, and procedural expertise:

• Haemodialysis initiation and management
• Peritoneal dialysis and home dialysis training
• Renal biopsy
• AV fistula-related procedures
• Tunnelled dialysis catheter insertion

Kidney Stone and Genetic Kidney Disease

Patients with recurrent kidney stones and inherited kidney disorders are assessed and managed with targeted diagnostic and treatment strategies:

• Kidney stone diagnosis and prevention
• Asymptomatic renal stone screening in diabetic patients
• Polycystic kidney disease management
• Genetic kidney disorder evaluation
• Recurrent stone former management

Credentials and Qualifications

• MBBS with Honours, Medical College, Kolkata, University of Calcutta (2003)
• MD Internal Medicine, PGIMER, Chandigarh (2008), Bronze Medal of Second Order
• DM Nephrology, PGIMER, Chandigarh (2010)
• FICP, Fellow of the Indian College of Physicians
• Preceptorship in ABO-Incompatible Kidney Transplantation, Tokyo, Japan
• Medical Registration, West Bengal Medical Council, No. 59294 (2003)

Dr Upal is a member of the Indian Society of Nephrology, International Society of Nephrology, American Society of Nephrology, European Renal Association, and the Indian College of Physicians.

Experience and Affiliations

Current

• Director, Team Nephrology, Manipal Hospitals, Mukundapur, Kolkata
• Consultant, Manipal Hospitals, Broadway, Kolkata
• Consultant, Manipal Hospitals, Dhakuria, Kolkata
• Consultant, Manipal Hospitals, Salt Lake, Kolkata
• Consultant, Manipal Hospitals, EM Bypass, Kolkata
• Consultant, Suraksha Clinic and Diagnostics, Newtown, Kolkata

Previous

• Director, Nephrology, Fortis Hospital Kidney Institute, Gariahat, Kolkata (2018 to 2025)
• Senior Consultant, Apollo Hospitals, Kolkata (2012 to 2018)
• Consultant, AMRI Hospitals, Kolkata (2008 to 2012)

Publications

• "Infusion of Autologous Bone Marrow Mononuclear Cells Leads to Transient Reduction in Proteinuria in Treatment Refractory Patients with Idiopathic Membranous Nephropathy", BMC Nephrology, 2013, Vol 14
• "Zygomycetes Peritonitis in Ambulatory Peritoneal Dialysis: Case Report and Review of Literature", Indian Journal of Nephrology, July 2014, Vol 24(4)
• "Higher Prevalence of Asymptomatic Renal Stones in Diabetic Population: Do We Need to Screen Routinely", International Journal of Scientific Research, May 2017, Vol 6(5)
• "A Comparative Study of Clinical Presentation of Scrub Typhus Patients Between Pre and Post-Monsoon Clusters in a Tertiary Care Hospital in Kolkata", Journal of the Indian Medical Association, April 2022, Vol 120(4)
• "A Study of Clinical Presentations of Chronic Lead Poisoning in Adults", Journal of the Indian Medical Association, August 2021, Vol 119(8)
• "A Comparative Study of Clinical Features and Severity of Dengue Outbreaks Between Two Successive Years in a Tertiary Care Hospital in Kolkata", Indian Journal of Basic and Applied Medical Research, December 2016, Vol 6(1)

Awards and Academic Contributions

• Manav Seva Samman, Governor of Chandigarh, 2012
• Bronze Medal of Second Order, PGIMER, Chandigarh, MD Internal Medicine, 2010
• Abirlal Memorial Gold Medal in Otorhinolaryngology, 2002
• Silver Medal in Pharmacology, 2001
• University Topper in Pharmacology and ENT
• Best Paper Award, Indian Society of Nephrology Conference, stem cell research in glomerulonephritis, 2015
• Chairman, Scientific Committee, East Zone Conference of the Indian Society of Nephrology, ISNEZCON, 2024
• Co-Organising Secretary, HOPECON 2025

Book an Appointment with Dr Upal Sengupta, Nephrologist in Kolkata

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