VenaSeal Varicose Veins Treatment

Medically Reviewed by
Dr. Aman Priya Khanna
VenaSeal Varicose Veins Treatment

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VenaSeal Varicose Veins Treatment
Medically Reviewed by Dr. Aman Priya Khanna Written by Dr Priyamvada Upadhyay

Book Appointment for VenaSeal Varicose Veins Treatment

According to a study by Shantonu Kumar Ghosh et al. in 2021, about 40-60% of females and 15-30% of males in India have varicose veins. The condition affects a large segment of the adult population and requires an effective solution. VenaSeal glue is a minimally invasive procedure that seals the affected veins with medical glue for immediate and long-term relief. 

VenaSeal is a varicose veins treatment that offers a less painful alternative to traditional methods. Moreover, this technique minimises recovery time. Continue reading to know more about the procedure. 

Procedure Name 

VenaSeal Vein Glue 

Conditions Treated 

Varicose veins, venous ulcers 

Benefits of Procedure 

Minimally invasive, reduced pain, quick recovery 

Treated By 

Vascular doctor 

What is VenaSeal Vein Glue?

VenaSeal glue is a medical adhesive used to close off varicose veins. This innovative treatment involves injecting the glue into the affected vein through a small catheter. Once the vein walls are sealed, blood is naturally rerouted to healthy veins. The sealed vein walls will harden through sclerosis and eventually get absorbed by the surrounding tissue.

Conditions Treated With VenaSeal Glue

VenaSeal glue is primarily used to treat conditions related to venous insufficiency, where veins have difficulty returning blood from the limbs to the heart. The problems treated with this procedure include:

  1. Varicose Veins: Enlarged, swollen, and twisting veins, often appearing blue or dark purple.

  2. Venous Ulcers: Open sores or wounds that occur due to improper functioning of valves inside the leg veins. 

Who needs the venaseal glue procedure?

Deciding the right varicose veins treatment involves careful consideration and expert advice. Individuals who benefit the most from the VenaSeal glue method include:

  1. Symptomatic Discomfort: Those experiencing pain, swelling, leg heaviness, and fatigue associated with varicose veins. It also speeds up ulcer healing and minimises the chances of recurrence. 

  2. Have Confirmed Venous Reflux: This is a condition in which blood flows backwards due to valve failure. The objective in such cases is to improve physical appearance. 

VenaSeal glue is not recommended for patients with certain conditions due to potential risks or complications. These include:

  1. Known allergies to cyanoacrylate (medical super-glue), as VenaSeal contains this substance

  2. Acute superficial thrombophlebitis (inflammation and blood clots form in veins close to the surface of the skin) 

  3. Thrombophlebitis migrans (recurrent blood clots and inflammation in the vein)

  4. Acute sepsis (severe or dramatic response of the immune system to an infection) 

VenaSeal Vein Glue Procedure

The VenaSeal treatment for varicose veins is performed at the doctor’s clinic. It usually takes 30-60 minutes to complete and includes the following steps:

  1. A small area around the vein is numbed with local anaesthetic for comfort during the procedure.

  2. The doctor makes a small incision near the affected vein and inserts a catheter into it under ultrasound guidance.

  3. VenaSeal glue is injected through the catheter inside the vein. A gentle pressure is applied to the vein for 30 seconds for the glue to bond with the walls.

  4. Applying glue and pressing the vein walls is repeated at 3 cm intervals along the complete length of the treated vein.

  5. After the adhesive has been applied, the catheter is carefully withdrawn.

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Before and on the Day of the VenaSeal Glue Procedure

Preparing for the VenaSeal procedure involves understanding what steps to take before and on the day of the treatment to ensure its success. Patients should follow their doctor’s instructions closely.  

Before the Procedure

This preparation phase is key to ensuring the patient is ready for the treatment. It involves the following steps: 




Detailed discussion about medical history and procedure 

Preparation Instructions 

  1. Medication adjustments 

  2. Wear loose-fitting clothes

Risk Evaluation 

  1. Allergies

  2. Risks vs benefits 



On the Day of the Procedure

Knowing what to expect can alleviate nerves and help patients feel more at ease. Generally, here’s what happens on the procedure day: 




As per the scheduled time 



Surgical Preparation 

  1. Briefing of the procedure 

  2. Cleaning of surgical site 

Physical Evaluation 

  1. Vitals check-up (blood pressure, breathing, heart rate, etc.) 

  2. Ultrasound mapping 

After Procedure and Recovery

After undergoing the VenaSeal for varicose veins treatment, individuals can return to their daily activities almost immediately, with minimal downtime. The following is what they can expect during recovery:

In Hospital Recovery 

After the procedure, the patients will rest in the recovery area. No hospital stay is required, so they can return home the same day. Before discharge, the doctor will provide home-care instructions as needed. 

At-home Recovery 

Following the procedure, patients experience minimal to no bruising and swelling. Once individuals return home, they will be advised to do the following: 

  1. Keeping the treated area clean and dry.

  2. Walking 30 minutes every day for the first two weeks after the treatment.

  3. Elevating legs to reduce swelling.

  4. Taking over-the-counter medications to manage any pain or discomfort.

  5. Avoiding heavy lifting or strenuous activities for a short period as advised by the doctor.

  6. Refraining from exposure to UV rays or sunlight for at least seven days post-procedure.

Patients may need to wear compression stockings for 3-7 days post-procedure to support healing. However, this is less common than other varicose vein treatments.

Benefits of VenaSeal Glue

The advantages offered by VenaSeal glue make it a preferred option for patients seeking an effective and less invasive treatment for varicose veins. The key benefits of the procedure include: 

  1. No General Anaesthesia: VenaSeal is typically performed under local anaesthesia, which makes it safer and avoids the risks associated with general anaesthesia.

  2. Reduced Pain: Compared to traditional varicose vein treatments, VenaSeal causes less discomfort and bruising during and after the procedure.

  3. Quick Recovery: People can return to their daily activities immediately or one day after the procedure. There is little to no downtime.

Risks of VenaSeal Vein Glue

The VenaSeal closure system is generally considered safe. However, like the traditional endovenous thermal ablation procedures, some adverse effects are associated with this technique. These include: 

  1. Allergic Reactions: Possible reactions to cyanoacrylates include hives, asthma, and hay fever.

  2. Bleeding: Occurring at the site of catheter insertion.

  3. Deep Vein Thrombosis (DVT): Formation of blood clots in deep veins.

  4. Leg Oedema: Swelling in the treated leg.

  5. Haematoma: Collection of blood outside blood vessels.

  6. Phlebitis: Inflammation of a vein.

  7. Superficial Thrombophlebitis: A blood clot in a vein just below the surface of the skin.

  8. Vascular Perforation: Breakage or piercing of a blood vessel.

Risks of Delaying VenaSeal Vein Glue Procedure

Delaying VenaSeal treatment for varicose veins can lead to a progression of symptoms and complications. Untreated varicose veins may worsen over time, increasing the risk of the following: 

  1. Discolouration of the skin, followed by painful ulcers 

  2. Blood clots in the veins located under the surface of the skin 

  3. Bleeding, caused by the bursting of veins close to the skin 

  4. Swelling in the leg 

Cost of VenaSeal Vein Glue 

The cost of VenaSeal vein glue treatment in India starts from ₹ 1,25,000 and can go up to ₹ 3,00,000. The prices can differ depending on several factors, including: 

  1. Severity and Number of Veins Treated: More complex or numerous varicose veins may require additional VenaSeal glue, impacting the cost.

  2. Practitioner’s Expertise: Experienced doctors may charge more for their services. 

  3. Type of Hospital: The prices are generally higher in multispeciality hospitals than in small facilities or clinics. 

  4. Geographic Location: The expenses can vary significantly depending on the city or region where the treatment is performed.

  5. Medical Tests: The final bill may add pre-treatment evaluations and post-treatment follow-ups. 

Procedure Name 

Estimated Cost Range 

VenaSeal Vein Glue 

₹ 1,25,000 - ₹ 3,00,000

Note: These prices are approximate. Patients are advised to consult HexaHealth experts for accurate prices. 


VenaSeal glue offers a cutting-edge solution for those struggling with varicose veins. The treatment combines efficacy with minimal discomfort. It stands out as a non-surgical option that requires no downtime. This makes it an attractive choice for patients seeking immediate improvement in their condition.

With HexaHealth, getting effective varicose veins treatment is made simpler. We help you find top healthcare facilities equipped with VenaSeal glue. Moreover, our team will assist you from consultation through recovery. So what are you waiting for? Get in touch with us TODAY!

Suggested Reads

1. Laser Treatment for Varicose Veins

2. Sclerotherapy for Varicose Veins

Frequently Asked Questions (FAQ)

VenaSeal vein glue is a medical adhesive to treat varicose veins. It permanently closes the affected veins, redirecting blood flow to healthy veins. This improves symptoms and appearance without surgery.


VenaSeal glue works for varicose veins treatment by being injected directly into the affected vein using a fine catheter. The glue seals the vein walls together so blood can reroute to healthy veins. As a result, the varicose condition is treated.


VenaSeal for varicose veins is a minimally invasive procedure that offers various advantages. These benefits include: 

  1. No general anaesthesia

  2. Minimal discomfort 

  3. No requirement for compression stockings post-treatment 

  4. Quick return to daily activities


Yes, VenaSeal glue is FDA-approved for the treatment of varicose veins. It is considered safe and effective for sealing veins and improving the symptoms and appearance of varicose veins.


Though rare, there are various risks associated with VenaSeal treatment. These include: 

  1. Allergic reactions

  2. Vein inflammation 

  3. Swelling in the leg 

  4. Bleeding 

  5. Infection


VenaSeal glue is designed to provide lasting results for varicose veins. Once applied, the glue seals the vein permanently.


VenaSeal glue has a high success rate, positioning it as a reliable varicose veins treatment option. According to the Indian VenaSeal Experience Study, the closure rate of the target vein was 98% at 6 months, 97% at 12 months, and 95% at 2 years.


The VenaSeal procedure takes about 30-60 minutes to complete. During the procedure, patients can expect the following: 

  1. A catheter is guided into the affected vein using ultrasound imaging. 

  2. VenaSeal glue is applied through the catheter. 

  3. The glue seals the vein walls upon contact. 

  4. Pressure is applied externally to ensure the vein remains closed as the glue sets.


VenaSeal does not have documented limitations regarding the type of varicose veins it can treat. However, its suitability varies from case to case, depending on the patient’s condition and the severity of the varicose veins.


VenaSeal treatment is generally not painful. Patients may feel minimal discomfort during the procedure. This is mainly a slight stinging sensation as the glue enters the vein. Local anaesthesia is used to numb the treatment area, enhancing patient comfort.


Yes, patients must take some precautions after VenaSeal treatment to ensure positive outcomes. These include: 

  1. Avoiding strenuous activities for a short period 

  2. Regular walking to promote good circulation 

  3. Keeping the area clean and dry


VenaSeal offers a less invasive alternative to sclerotherapy or laser treatment with no need for multiple injections or heat application. It requires fewer post-treatment restrictions and has a quick recovery time. However, the choice of treatment should be based on individual case assessment.


The cost of VenaSeal glue treatment can vary between  ₹ 1,25,000 to ₹ 3,00,000, based on location, healthcare facility, and the extent of treatment needed. However, these prices are estimates. Consult HexaHealth experts for accurate expenses.


Although VenaSeal offers various benefits, it is not suited for everyone. Individuals who are not a candidate for the procedure include those with: 

  1. Allergies to cyanoacrylate adhesives.

  2. Acute superficial thrombophlebitis (a blood clot in a vein under the skin).

  3. Thrombophlebitis migrans (recurring blood clots in the vein).

  4. Acute sepsis (a serious immune system response to an infection).


A potential disadvantage of VenaSeal is its cost, which may be higher than other varicose vein treatments. Some other drawbacks of the procedure are as follows: 

  1. Other side branches of the main refluxing vein may need additional treatments like sclerotherapy. 

  2. Though rare, the treatment can cause allergic reactions in patients.


VenaSeal glue treatment is considered safe, with a low risk of complications. The procedure is performed under local anaesthesia, and most patients experience minimal side effects. It is FDA-approved, indicating rigorous testing and approval for safety and effectiveness.


After VenaSeal treatment, the immediate effect is the cessation of blood flow through the sealed vein. The blood gets redirected through healthier veins, alleviating symptoms and improving venous circulation. Eventually, the treated vein hardens and gets absorbed by the surrounding tissue.



All the articles on HexaHealth are supported by verified medically-recognized sources such as; peer-reviewed academic research papers, research institutions, and medical journals. Our medical reviewers also check references of the articles to prioritize accuracy and relevance. Refer to our detailed editorial policy for more information.

  1. Ghosh SK, Al Mamun A, Majumder A. Clinical Presentation of Varicose Veins. Indian Journal of Surgery. 2021 May
  2. VenaSeal Vein Glue - Varicose Veins Treatment | Vein Health [Internet]. [cited 2024 Apr 10]. link
  3. Publishing L, CVDTeam. VenaSealTM closure system for varicose veins [Internet]. Servier - Phlebolymphology. 2019 [cited 2024 Apr 10].link
  4. VenaSeal - Innovative Varicose Vein Treatment | Sunshine Coast Vascular [Internet]. Dr Rebecca Magee. [cited 2024 Apr 10].link
  5. Kapadia DS. VenaSeal: Painless Varicose Vein Glue Treatment [Internet]. Dr. Sumit Kapadia. 2023 [cited 2024 Apr 10].link
  6. VenaSeal TM Closure System Product Code: VS-402 [Internet].link
  7. Medtronic. VenaSeal Procedure - Vein Disease Treatments [Internet].
  8. Mayo Clinic. Varicose veins - symptoms and causes [Internet]. Mayo Clinic.
  9. Shah RA, Bedi SV, Yadav RA, Agarwal S, Satwik A, Srivastava A, et al. Indian VenaSealTM Experience Study Extension: Outcomes of Nonthermal, Nontumescent Endovenous Ablation (VenaSealTM) for the Treatment of Truncal Reflux in Varicose Vein Disease – An Indian Perspective with 2-Year Follow-up. Indianlink
Disclaimer: The information provided here is for educational and learning purposes only. It doesn't cover every medical condition and might not be relevant to your personal situation. This information isn't medical advice, isn't meant for diagnosing any condition, and shouldn't replace talking to a certified medical or healthcare professional.


Dr. Aman Priya Khanna

Dr. Aman Priya Khanna

MBBS, DNB General Surgery, Fellowship in Minimal Access Surgery, FIAGES

12 Years Experience

Dr Aman Priya Khanna is a well-known General Surgeon, Proctologist and Bariatric Surgeon currently associated with HealthFort Clinic, Health First Multispecialty Clinic in Delhi. He has 12 years of experience in General Surgery and worke...View More


Dr Priyamvada Upadhyay

Dr Priyamvada Upadhyay

Master of Public Health (MPH) from Academy of Scientific and Innovative Research (AcSIR) - 2024 | Bachelor of Dental Surgery (BDS) from Rajasthan University of Health Sciences (RUHS) - 2020

4 Years Experience

With a comprehensive academic background in BDS (Bachelor of Dental Surgery) followed by an MPH (Master of Public Health), she brings a unique blend of clinical expertise and public health knowledge to the table. H...View More

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