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A pilonidal sinus or cyst (पिलोनाइडल साइनस/गांठ) is a circular fluid-filled sac generally present beneath the skin in the lower back region or near the crease (line) of the buttocks. It accumulates skin debris, hair and dust particles. It is also known as pilonidal cyst disease. It can be symptom-free or cause much pain and discomfort when infected, requiring urgent medical attention and treatment.